US Scripts MD vs Sesame Care
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
US Scripts MD vs Sesame Care: Overview
Choosing between US Scripts MD and Sesame Care for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
US Scripts MD offers both semaglutide and tirzepatide at $299/month with a rating of 7/10. Sesame Care also provides both semaglutide and tirzepatide at $59/month with a 8.7/10 rating.
The price difference of $240/month is significant - Sesame Care is the more budget-friendly option, while US Scripts MD positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$240/mo
Rating Difference
1.7
Winner
Sesame Care
Best For
Budget
US Scripts MD
View full US Scripts MD review →Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide
Pros
- ✓One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
- ✓No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
- ✓Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
- ✓Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
- ✓An injection kit with spare syringes is included in every shipment
- ✓Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
- ✓24/7 access to board-certified doctor support is advertised
- ✓You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
- ✓A $100 discount on the first month of weight-loss treatment
Cons
- ✗Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
- ✗The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
- ✗Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
- ✗The medication is compounded and not FDA-approved
- ✗The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
- ✗The dispensing pharmacy is not named
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗No published phone number
Sesame Care
View full Sesame Care review →Rating
8.7/10Better
Monthly Price
$59Cheaper
Medications
semaglutidetirzepatideorforglipron
Pros
- ✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
- ✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
- ✓Every medication offered is FDA-approved and branded - no compounded product is involved
- ✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
- ✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
- ✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
- ✓A full refund is available if you cancel at least three hours before your first visit
- ✓The wider marketplace lets you compare individual providers on price, with appointments from $37
Cons
- ✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
- ✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
- ✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
- ✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
- ✗Monthly subscribers are not refunded for months already paid, even if unused
- ✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
- ✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service
Feature-by-feature comparison
| Feature | US Scripts MD | Sesame Care |
|---|---|---|
| Monthly Price | $299 | $59 |
| Rating | 7/10 | 8.7/10 |
| Medications | liraglutide, semaglutide | semaglutide, tirzepatide, orforglipron |
| Insurance Accepted | No | Yes |
| Support Hours | Company advertises 24/7 access to partnering board-certified doctors | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | No |
| Shipping Speed | Free overnight shipping in temperature-controlled packaging | Filled at your pharmacy; not shipped by Sesame |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | 24/7 access to partnering board-certified doctors for questions and support | Ongoing video visits, labs and messaging with a dedicated provider |
| Money-back Guarantee | Full refund if the medical providers determine you are not a fit for the programme | Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid |
| Cancellation Policy | Cancel any time before your order ships; no contracts | Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded |
Which should you choose?
Choose US Scripts MD if you:
- →Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1
Choose Sesame Care if you:
- →Want to save $240/month with a more affordable option
- →Prefer a higher-rated service (8.7/10 vs 7/10)
- →Want more medication options to choose from
- →Need insurance coverage for your treatment
- →Want personalized coaching support included
- →Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
Website previews
US Scripts MD
Sesame Care
Our recommendation
Sesame Care comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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