Winona vs Sesame Care
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Winona vs Sesame Care: Overview
Choosing between Winona and Sesame Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Winona offers both semaglutide and tirzepatide at $89/month with a rating of 8.4/10. Sesame Care also provides both semaglutide and tirzepatide at $59/month with a 8.7/10 rating.
With only a $30/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$30/mo
Rating Difference
0.3
Winner
Sesame Care
Best For
Budget
Winona
View full Winona review →Rating
8.4/10
Monthly Price
$89
Medications
bioidentical estradiolprogesteroneestriolDHEAsildenafilminoxidil
Pros
- ✓The full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked July 28, 2026)
- ✓Multiple delivery routes are offered - patch, body cream, vaginal cream, tablet and capsule - so treatment can be matched to preference rather than to whatever the company happens to stock
- ✓Winona owns its own 503A compounding pharmacies rather than outsourcing to a partner, which gives it direct control over formulation and consistency
- ✓Its pharmacy page explains the 503A/503B distinction correctly and states that 503A pharmacies are regulated by State Boards of Pharmacy, not the FDA - an accurate description that competitors routinely overstate
- ✓Roughly 8,000 Trustpilot reviews at 4.6, with 99% of negative reviews answered and a typical reply time under 24 hours
- ✓The rating advertised on site matches the rating on the public Trustpilot profile
- ✓The initial visit is free, so you can be assessed before paying for treatment
- ✓Editorial content carries numbered citations rather than unsourced assertions, and the site runs a public subreddit alongside a help centre and published phone number
- ✓HSA/FSA eligible, with a dedicated page explaining eligibility
- ✓Adjacent products are priced transparently too - DHEA from $27 per 3-month supply, sildenafil arousal cream at $79 per order, minoxidil hair serum at $150 per 3-month supply
Cons
- ✗Everything Winona dispenses is compounded in its own 503A pharmacies, which means it is not FDA-approved and has not been evaluated by the FDA for safety, efficacy or quality. The site explains 503A status clearly but does not foreground the 'not FDA-approved' consequence as plainly
- ✗Pharmaceutical products cannot be returned, per the terms - so once a prescription ships, you own it
- ✗The terms carry a mandatory arbitration clause on an individual basis with a class-action waiver, set out in capitals at the top of the document
- ✗Every headline price is a 'from' figure, so the actual monthly cost depends on the dose your clinician prescribes and is not knowable before the consultation
- ✗The hormone therapy explainer describes HRT as 'scientifically proven to be the safest, most effective treatment' for menopause symptoms. It is cited, but that is a strong framing for a therapy whose risk profile still depends heavily on age, time since menopause and personal history
- ✗Trustpilot notes Winona invites customers to review, which tends to lift scores relative to organic-only profiles, and that it may use AI-assisted replies
- ✗Systemic estrogen is not appropriate for everyone - women with a history of breast or endometrial cancer, unexplained vaginal bleeding, blood clots, stroke or liver disease should not start it without specialist input
- ✗Compounded hormone therapy in general lacks the long-term outcome data that exists for FDA-approved products, so the evidence cited for HRT as a class does not transfer automatically to these specific preparations
Sesame Care
View full Sesame Care review →Rating
8.7/10Better
Monthly Price
$59Cheaper
Medications
semaglutidetirzepatideorforglipron
Pros
- ✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
- ✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
- ✓Every medication offered is FDA-approved and branded - no compounded product is involved
- ✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
- ✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
- ✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
- ✓A full refund is available if you cancel at least three hours before your first visit
- ✓The wider marketplace lets you compare individual providers on price, with appointments from $37
Cons
- ✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
- ✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
- ✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
- ✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
- ✗Monthly subscribers are not refunded for months already paid, even if unused
- ✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
- ✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service
Feature-by-feature comparison
| Feature | Winona | Sesame Care |
|---|---|---|
| Monthly Price | $89 | $59 |
| Rating | 8.4/10 | 8.7/10 |
| Medications | bioidentical estradiol, progesterone, estriol, DHEA, sildenafil, minoxidil | semaglutide, tirzepatide, orforglipron |
| Insurance Accepted | No | Yes |
| Support Hours | Help centre and chat available; hours not published | Not published |
| Live Chat | Available | No |
| Free Shipping | Yes | No |
| Shipping Speed | Shipped to your door after clinician review; free shipping included | Filled at your pharmacy; not shipped by Sesame |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | Ongoing clinician access through the patient portal; cadence not published | Ongoing video visits, labs and messaging with a dedicated provider |
| Money-back Guarantee | None published; pharmaceutical products cannot be returned. A separate cancellation and refund policy governs subscriptions | Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid |
| Cancellation Policy | Subscriptions can be cancelled from your account; a separate cancellation policy governs when it takes effect | Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded |
Which should you choose?
Choose Winona if you:
- →Want more medication options to choose from
- →Value: the full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked july 28, 2026)
Choose Sesame Care if you:
- →Want to save $30/month with a more affordable option
- →Prefer a higher-rated service (8.7/10 vs 8.4/10)
- →Need insurance coverage for your treatment
- →Want personalized coaching support included
- →Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
Website previews
Winona
Sesame Care
Our recommendation
Sesame Care comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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