Yucca Health vs PlushCare
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Yucca Health vs PlushCare: Overview
Choosing between Yucca Health and PlushCare for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Yucca Health offers both semaglutide and tirzepatide at $146/month with a rating of 8/10. PlushCare also provides both semaglutide and tirzepatide at $20/month with a 8.5/10 rating.
The price difference of $126/month is significant - PlushCare is the more budget-friendly option, while Yucca Health positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$126/mo
Rating Difference
0.5
Winner
PlushCare
Best For
Budget
Yucca Health
View full Yucca Health review →Rating
8/10
Monthly Price
$146
Medications
semaglutidetirzepatide
Pros
- ✓The FAQ publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked July 27, 2026
- ✓A lifetime price lock is offered under code YUCCA4LIFE at $146/mo, which if honoured protects against the mid-treatment increases common in this category
- ✓Trustpilot rating of 4.6 across 1,197 reviews, closely matching the figure shown on site
- ✓The compounded, not-FDA-approved status is spelled out in full, including the point that these drugs do not undergo FDA review for manufacturing quality
- ✓The whole site is available in Spanish, which almost no other provider in this category offers
- ✓Licensed providers in all 50 states, US-licensed pharmacies and free expedited shipping
- ✓Refund policy and shipping policy are both published as separate documents
- ✓NAD+ and sermorelin are available if you want more than weight care, without being bundled into the GLP-1 price
Cons
- ✗A developer's note is rendering inside the live page. Between the product cards the text reads: 'the SSR pass triggers an "Invalid hook call" because the React renderer dispatcher is null in the Cloudflare Workers SSR pipeline'. An engineering comment left in production is not reassuring on a site handling prescriptions
- ✗Secondary product pricing contradicts itself: NAD+ is shown as 'Starting at $158' in one block and 'As low as $215' in another, and sermorelin as both '$158' and '$199'
- ✗'Pricing is shared after intake once eligibility is confirmed' sits directly above a FAQ answer that then states all the prices, so the site cannot decide whether pricing is gated
- ✗Social-proof counters disagree with each other - one product card claims '1000+ Patients enrolled in last 7 days' while others on the same page say '100+'
- ✗Describing compounded products as having 'the same active pharmaceutical ingredients as brand-name drugs' is the claim type the FDA cited in a February 2026 warning letter to a competitor, even though Yucca does disclaim FDA approval immediately afterwards
- ✗The 'for life' price lock has no published terms explaining what would void it
- ✗No published phone number or support hours
- ✗No BBB profile or complaint record to check against the Trustpilot score
PlushCare
View full PlushCare review →Rating
8.5/10Better
Monthly Price
$20Cheaper
Medications
semaglutidetirzepatideliraglutide
Pros
- ✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
- ✓Membership is $19.99/month with the first month free, and there is no minimum commitment
- ✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
- ✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
- ✓A full refund is offered if the doctor is unable to treat you
- ✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
- ✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
- ✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure
Cons
- ✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
- ✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
- ✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
- ✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
- ✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
- ✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
- ✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
- ✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site
Feature-by-feature comparison
| Feature | Yucca Health | PlushCare |
|---|---|---|
| Monthly Price | $146 | $20 |
| Rating | 8/10 | 8.5/10 |
| Medications | semaglutide, tirzepatide | semaglutide, tirzepatide, liraglutide |
| Insurance Accepted | No | Yes |
| Support Hours | Not published | Video visits available 24/7 |
| Live Chat | No | No |
| Free Shipping | Yes | No |
| Shipping Speed | Free expedited shipping claimed | Filled at your pharmacy; not shipped by PlushCare |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Not published | Ongoing management with a board-certified primary care physician |
| Money-back Guarantee | A refund policy is published as a separate document; no blanket money-back guarantee is advertised | Full refund if the doctor is unable to treat you; medication and lab costs are never included |
| Cancellation Policy | Published separately; the lifetime price lock has no stated conditions | Cancel anytime, no minimum commitment; first month of membership is free |
Which should you choose?
Choose Yucca Health if you:
- →Value: the faq publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked july 27, 2026
Choose PlushCare if you:
- →Want to save $126/month with a more affordable option
- →Prefer a higher-rated service (8.5/10 vs 8/10)
- →Want more medication options to choose from
- →Need insurance coverage for your treatment
- →Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit
Website previews
Yucca Health
PlushCare
Our recommendation
PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with PlushCareRelated comparisons
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