Yucca Health vs Shameless Care
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Yucca Health vs Shameless Care: Overview
Choosing between Yucca Health and Shameless Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Yucca Health offers both semaglutide and tirzepatide at $146/month with a rating of 8/10. Shameless Care also provides both semaglutide and tirzepatide at $109/month with a 8/10 rating.
With only a $37/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$37/mo
Rating Difference
0.0
Winner
Shameless Care
Best For
Budget
Yucca Health
View full Yucca Health review →Rating
8/10
Monthly Price
$146
Medications
semaglutidetirzepatide
Pros
- ✓The FAQ publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked July 27, 2026
- ✓A lifetime price lock is offered under code YUCCA4LIFE at $146/mo, which if honoured protects against the mid-treatment increases common in this category
- ✓Trustpilot rating of 4.6 across 1,197 reviews, closely matching the figure shown on site
- ✓The compounded, not-FDA-approved status is spelled out in full, including the point that these drugs do not undergo FDA review for manufacturing quality
- ✓The whole site is available in Spanish, which almost no other provider in this category offers
- ✓Licensed providers in all 50 states, US-licensed pharmacies and free expedited shipping
- ✓Refund policy and shipping policy are both published as separate documents
- ✓NAD+ and sermorelin are available if you want more than weight care, without being bundled into the GLP-1 price
Cons
- ✗A developer's note is rendering inside the live page. Between the product cards the text reads: 'the SSR pass triggers an "Invalid hook call" because the React renderer dispatcher is null in the Cloudflare Workers SSR pipeline'. An engineering comment left in production is not reassuring on a site handling prescriptions
- ✗Secondary product pricing contradicts itself: NAD+ is shown as 'Starting at $158' in one block and 'As low as $215' in another, and sermorelin as both '$158' and '$199'
- ✗'Pricing is shared after intake once eligibility is confirmed' sits directly above a FAQ answer that then states all the prices, so the site cannot decide whether pricing is gated
- ✗Social-proof counters disagree with each other - one product card claims '1000+ Patients enrolled in last 7 days' while others on the same page say '100+'
- ✗Describing compounded products as having 'the same active pharmaceutical ingredients as brand-name drugs' is the claim type the FDA cited in a February 2026 warning letter to a competitor, even though Yucca does disclaim FDA approval immediately afterwards
- ✗The 'for life' price lock has no published terms explaining what would void it
- ✗No published phone number or support hours
- ✗No BBB profile or complaint record to check against the Trustpilot score
Shameless Care
View full Shameless Care review →Rating
8/10
Monthly Price
$109Cheaper
Medications
sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline
Pros
- ✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
- ✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
- ✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
- ✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
- ✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
- ✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
- ✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
- ✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
- ✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
- ✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost
Cons
- ✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
- ✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
- ✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
- ✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
- ✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
- ✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
- ✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
- ✗Not available in all 50 states - the site states 49
- ✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron
Feature-by-feature comparison
| Feature | Yucca Health | Shameless Care |
|---|---|---|
| Monthly Price | $146 | $109 |
| Rating | 8/10 | 8/10 |
| Medications | semaglutide, tirzepatide | sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline |
| Insurance Accepted | No | No |
| Support Hours | Not published | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free expedited shipping claimed | Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Not published | Board-certified physician assigned from start to finish; ongoing cadence not published |
| Money-back Guarantee | A refund policy is published as a separate document; no blanket money-back guarantee is advertised | Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published |
| Cancellation Policy | Published separately; the lifetime price lock has no stated conditions | No subscriptions - every purchase is one-off, so there is nothing to cancel |
Which should you choose?
Choose Yucca Health if you:
- →Value: the faq publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked july 27, 2026
Choose Shameless Care if you:
- →Want to save $37/month with a more affordable option
- →Want more medication options to choose from
- →Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)
Website previews
Yucca Health
Shameless Care
Our recommendation
Shameless Care offers better value at $109/month while maintaining strong ratings. It also provides multiple medication options including both semaglutide and tirzepatide.
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