Yucca Health vs Winona
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Yucca Health vs Winona: Overview
Choosing between Yucca Health and Winona for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Yucca Health offers both semaglutide and tirzepatide at $146/month with a rating of 8/10. Winona also provides both semaglutide and tirzepatide at $89/month with a 8.4/10 rating.
The price difference of $57/month is significant - Winona is the more budget-friendly option, while Yucca Health positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$57/mo
Rating Difference
0.4
Winner
Winona
Best For
Budget
Yucca Health
View full Yucca Health review →Rating
8/10
Monthly Price
$146
Medications
semaglutidetirzepatide
Pros
- ✓The FAQ publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked July 27, 2026
- ✓A lifetime price lock is offered under code YUCCA4LIFE at $146/mo, which if honoured protects against the mid-treatment increases common in this category
- ✓Trustpilot rating of 4.6 across 1,197 reviews, closely matching the figure shown on site
- ✓The compounded, not-FDA-approved status is spelled out in full, including the point that these drugs do not undergo FDA review for manufacturing quality
- ✓The whole site is available in Spanish, which almost no other provider in this category offers
- ✓Licensed providers in all 50 states, US-licensed pharmacies and free expedited shipping
- ✓Refund policy and shipping policy are both published as separate documents
- ✓NAD+ and sermorelin are available if you want more than weight care, without being bundled into the GLP-1 price
Cons
- ✗A developer's note is rendering inside the live page. Between the product cards the text reads: 'the SSR pass triggers an "Invalid hook call" because the React renderer dispatcher is null in the Cloudflare Workers SSR pipeline'. An engineering comment left in production is not reassuring on a site handling prescriptions
- ✗Secondary product pricing contradicts itself: NAD+ is shown as 'Starting at $158' in one block and 'As low as $215' in another, and sermorelin as both '$158' and '$199'
- ✗'Pricing is shared after intake once eligibility is confirmed' sits directly above a FAQ answer that then states all the prices, so the site cannot decide whether pricing is gated
- ✗Social-proof counters disagree with each other - one product card claims '1000+ Patients enrolled in last 7 days' while others on the same page say '100+'
- ✗Describing compounded products as having 'the same active pharmaceutical ingredients as brand-name drugs' is the claim type the FDA cited in a February 2026 warning letter to a competitor, even though Yucca does disclaim FDA approval immediately afterwards
- ✗The 'for life' price lock has no published terms explaining what would void it
- ✗No published phone number or support hours
- ✗No BBB profile or complaint record to check against the Trustpilot score
Winona
View full Winona review →Rating
8.4/10Better
Monthly Price
$89Cheaper
Medications
bioidentical estradiolprogesteroneestriolDHEAsildenafilminoxidil
Pros
- ✓The full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked July 28, 2026)
- ✓Multiple delivery routes are offered - patch, body cream, vaginal cream, tablet and capsule - so treatment can be matched to preference rather than to whatever the company happens to stock
- ✓Winona owns its own 503A compounding pharmacies rather than outsourcing to a partner, which gives it direct control over formulation and consistency
- ✓Its pharmacy page explains the 503A/503B distinction correctly and states that 503A pharmacies are regulated by State Boards of Pharmacy, not the FDA - an accurate description that competitors routinely overstate
- ✓Roughly 8,000 Trustpilot reviews at 4.6, with 99% of negative reviews answered and a typical reply time under 24 hours
- ✓The rating advertised on site matches the rating on the public Trustpilot profile
- ✓The initial visit is free, so you can be assessed before paying for treatment
- ✓Editorial content carries numbered citations rather than unsourced assertions, and the site runs a public subreddit alongside a help centre and published phone number
- ✓HSA/FSA eligible, with a dedicated page explaining eligibility
- ✓Adjacent products are priced transparently too - DHEA from $27 per 3-month supply, sildenafil arousal cream at $79 per order, minoxidil hair serum at $150 per 3-month supply
Cons
- ✗Everything Winona dispenses is compounded in its own 503A pharmacies, which means it is not FDA-approved and has not been evaluated by the FDA for safety, efficacy or quality. The site explains 503A status clearly but does not foreground the 'not FDA-approved' consequence as plainly
- ✗Pharmaceutical products cannot be returned, per the terms - so once a prescription ships, you own it
- ✗The terms carry a mandatory arbitration clause on an individual basis with a class-action waiver, set out in capitals at the top of the document
- ✗Every headline price is a 'from' figure, so the actual monthly cost depends on the dose your clinician prescribes and is not knowable before the consultation
- ✗The hormone therapy explainer describes HRT as 'scientifically proven to be the safest, most effective treatment' for menopause symptoms. It is cited, but that is a strong framing for a therapy whose risk profile still depends heavily on age, time since menopause and personal history
- ✗Trustpilot notes Winona invites customers to review, which tends to lift scores relative to organic-only profiles, and that it may use AI-assisted replies
- ✗Systemic estrogen is not appropriate for everyone - women with a history of breast or endometrial cancer, unexplained vaginal bleeding, blood clots, stroke or liver disease should not start it without specialist input
- ✗Compounded hormone therapy in general lacks the long-term outcome data that exists for FDA-approved products, so the evidence cited for HRT as a class does not transfer automatically to these specific preparations
Feature-by-feature comparison
| Feature | Yucca Health | Winona |
|---|---|---|
| Monthly Price | $146 | $89 |
| Rating | 8/10 | 8.4/10 |
| Medications | semaglutide, tirzepatide | bioidentical estradiol, progesterone, estriol, DHEA, sildenafil, minoxidil |
| Insurance Accepted | No | No |
| Support Hours | Not published | Help centre and chat available; hours not published |
| Live Chat | No | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free expedited shipping claimed | Shipped to your door after clinician review; free shipping included |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Not published | Ongoing clinician access through the patient portal; cadence not published |
| Money-back Guarantee | A refund policy is published as a separate document; no blanket money-back guarantee is advertised | None published; pharmaceutical products cannot be returned. A separate cancellation and refund policy governs subscriptions |
| Cancellation Policy | Published separately; the lifetime price lock has no stated conditions | Subscriptions can be cancelled from your account; a separate cancellation policy governs when it takes effect |
Which should you choose?
Choose Yucca Health if you:
- →Value: the faq publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked july 27, 2026
Choose Winona if you:
- →Want to save $57/month with a more affordable option
- →Prefer a higher-rated service (8.4/10 vs 8/10)
- →Want more medication options to choose from
- →Value: the full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked july 28, 2026)
Website previews
Yucca Health
Winona
Our recommendation
Winona comes out ahead with a higher rating of 8.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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