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Zepbound vs Enhance MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Zepbound vs Enhance MD: Overview

Choosing between Zepbound and Enhance MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Zepbound focuses on tirzepatide at $450/month with a rating of 9.3/10. Enhance MD also provides both semaglutide and tirzepatide at $212/month with a 7.7/10 rating.

The price difference of $238/month is significant - Enhance MD is the more budget-friendly option, while Zepbound positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$238/mo

Rating Difference

1.6

Winner

Zepbound

Best For

Quality

Zepbound

View full Zepbound review →

Rating

9.3/10Better

Monthly Price

$450

Medications

tirzepatide

Pros

✓FDA-approved for chronic weight management
✓Weekly injection
✓Superior weight loss results (~21% average)
✓Same active ingredient as Mounjaro
✓Dual GIP/GLP-1 receptor agonist

Cons

✗Requires prescription and medical supervision
✗Can cause GI side effects
✗High cost without insurance coverage
✗Not available in all pharmacies

Choose Zepbound

Enhance MD

View full Enhance MD review →

Rating

7.7/10

Monthly Price

$212Cheaper

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

Feature-by-feature comparison

Feature	Zepbound	Enhance MD
Monthly Price	$450	$212
Rating	9.3/10	7.7/10
Medications	tirzepatide	semaglutide, tirzepatide
Insurance Accepted	Yes	No
Support Hours	Mon-Fri 8AM-8PM ET	Not published
Live Chat	No	No
Free Shipping	No	Yes
Shipping Speed	Varies by pharmacy	Medication shipped every 12 weeks
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	As prescribed by physician	Ongoing provider care and support included
Money-back Guarantee	Savings card available for eligible patients	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding
Cancellation Policy	Prescription-based, consult doctor	Plans run monthly or in 3+ month blocks; no separate cancellation policy published

Which should you choose?

Choose Zepbound if you:

→Prefer a higher-rated service (9.3/10 vs 7.7/10)
→Need insurance coverage for your treatment
→Value: fda-approved for chronic weight management

Get started with Zepbound

Choose Enhance MD if you:

→Want to save $238/month with a more affordable option
→Want more medication options to choose from
→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Website previews

Zepbound

Zepbound website

Enhance MD

Enhance MD website

Our recommendation

Zepbound comes out ahead with a higher rating of 9.3/10.

Get started with Zepbound

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