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Zepbound vs TMates

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Zepbound vs TMates: Overview

Choosing between Zepbound and TMates for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Zepbound focuses on tirzepatide at $450/month with a rating of 9.3/10. TMates also provides both semaglutide and tirzepatide at $249/month with a 7.8/10 rating.

The price difference of $201/month is significant - TMates is the more budget-friendly option, while Zepbound positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$201/mo

Rating Difference

1.5

Winner

Zepbound

Best For

Quality

Zepbound

View full Zepbound review →

Rating

9.3/10Better

Monthly Price

$450

Medications

tirzepatide

Pros

✓FDA-approved for chronic weight management
✓Weekly injection
✓Superior weight loss results (~21% average)
✓Same active ingredient as Mounjaro
✓Dual GIP/GLP-1 receptor agonist

Cons

✗Requires prescription and medical supervision
✗Can cause GI side effects
✗High cost without insurance coverage
✗Not available in all pharmacies

Choose Zepbound

TMates

View full TMates review →

Rating

7.8/10

Monthly Price

$249Cheaper

Medications

semaglutidetirzepatide

Pros

✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
✓Both injectable and oral formats are offered at the same published prices
✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms

Cons

✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
✗No published customer phone number, support email or support hours
✗No BBB profile or complaint record to check

Feature-by-feature comparison

Feature	Zepbound	TMates
Monthly Price	$450	$249
Rating	9.3/10	7.8/10
Medications	tirzepatide	semaglutide, tirzepatide
Insurance Accepted	Yes	No
Support Hours	Mon-Fri 8AM-8PM ET	Not published
Live Chat	No	No
Free Shipping	No	Yes
Shipping Speed	Varies by pharmacy	Free shipping; timeframe not published
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	As prescribed by physician	Ongoing provider support included
Money-back Guarantee	Savings card available for eligible patients	None published
Cancellation Policy	Prescription-based, consult doctor	Cancel anytime, but multi-month plans are paid upfront

Which should you choose?

Choose Zepbound if you:

→Prefer a higher-rated service (9.3/10 vs 7.8/10)
→Need insurance coverage for your treatment
→Value: fda-approved for chronic weight management

Get started with Zepbound

Choose TMates if you:

→Want to save $201/month with a more affordable option
→Want more medication options to choose from
→Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026

Get started with TMates

Website previews

Zepbound

Zepbound website

TMates

TMates website

Our recommendation

Zepbound comes out ahead with a higher rating of 9.3/10.

Get started with Zepbound

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