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Enhance MD vs MadeMed

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Enhance MD vs MadeMed: Overview

Choosing between Enhance MD and MadeMed for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Enhance MD offers both semaglutide and tirzepatide at $212/month with a rating of 7.7/10. MadeMed also provides both semaglutide and tirzepatide at $239/month with a 7.3/10 rating.

With only a $27/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$27/mo

Rating Difference

0.4

Winner

Enhance MD

Best For

Budget

Enhance MD

View full Enhance MD review →

Rating

7.7/10Better

Monthly Price

$212Cheaper

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

MadeMed

View full MadeMed review →

Rating

7.3/10

Monthly Price

$239

Medications

semaglutidetirzepatide

Pros

✓The compounded disclaimer is explicit and sits on the product page itself, not in a distant footer
✓It directs patients to the FDA's adverse event reporting line (1-800-FDA-1088), which almost no competitor does
✓A real customer phone number is published rather than a contact form alone
✓Both semaglutide and tirzepatide are offered in injectable and oral forms
✓Quarterly billing at the starting dose is inexpensive - $239 per refill billed every three months for injectable semaglutide, and $399 for injectable tirzepatide (checked July 27, 2026)
✓The pricing footnote is honest about what it covers: 'Advertised pricing reflects the starting dosage'
✓Peptide and NAD+ lines are available alongside weight care

Cons

✗The monthly purchase option displays a price of '$0*/month'. On the primary buying path for the flagship product, the price simply does not render
✗Pricing is not flat across doses. The footnote states 'Actual price depends on the dosage prescribed by your provider', so the advertised figure applies only at the starting dose and rises as you titrate up - the opposite of the flat-price model most competitors offer, and a significant cost risk over a year
✗The '4.8/5' rating shown on product pages has no traceable source, and no Trustpilot profile exists for the domain
✗The homepage is effectively a navigation shell - it carries menus and a phone number but almost no content, pricing or explanation
✗Product pages are only reachable at bare paths such as /injectable-semaglutide; the more conventional /products/ and /weight-loss/ paths return empty shells
✗No refund or cancellation policy could be found beyond a 'Returns' link
✗No support hours are published, and there is no independent complaint record of any kind
✗Because the real cost depends on the dose you end up on, you cannot work out what a year of treatment will cost before signing up

Feature-by-feature comparison

Feature	Enhance MD	MadeMed
Monthly Price	$212	$239
Rating	7.7/10	7.3/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Medication shipped every 12 weeks	Not published
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing provider care and support included	Board-certified physician review; follow-up frequency not published
Money-back Guarantee	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding	None published; only a 'Returns' link is provided
Cancellation Policy	Plans run monthly or in 3+ month blocks; no separate cancellation policy published	Not published; billing is monthly or quarterly per refill

Which should you choose?

Choose Enhance MD if you:

→Want to save $27/month with a more affordable option
→Prefer a higher-rated service (7.7/10 vs 7.3/10)
→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Choose MadeMed if you:

→Value: the compounded disclaimer is explicit and sits on the product page itself, not in a distant footer

Get started with MadeMed

Website previews

Enhance MD

Enhance MD website

MadeMed

MadeMed website

Our recommendation

Enhance MD comes out ahead with a higher rating of 7.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Enhance MD

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