Enhance MD vs Sequence (now WeightWatchers Clinic)
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Enhance MD vs Sequence (now WeightWatchers Clinic): Overview
Choosing between Enhance MD and Sequence (now WeightWatchers Clinic) for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Enhance MD offers both semaglutide and tirzepatide at $212/month with a rating of 7.7/10. Sequence (now WeightWatchers Clinic) also provides both semaglutide and tirzepatide at $249/month with a 7.5/10 rating.
With only a $37/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$37/mo
Rating Difference
0.2
Winner
Enhance MD
Best For
Budget
Enhance MD
View full Enhance MD review →Rating
7.7/10Better
Monthly Price
$212Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
- ✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
- ✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
- ✓Product images are labelled 'Not actual vial - For marketing purposes only'
- ✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
- ✓Medication ships quarterly, so there are fewer delivery events to manage
- ✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly
Cons
- ✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
- ✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
- ✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
- ✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
- ✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
- ✗No published customer phone number or support hours
- ✗No BBB profile or independent complaint record to check
- ✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate
Sequence (now WeightWatchers Clinic)
View full Sequence (now WeightWatchers Clinic) review →Rating
7.5/10
Monthly Price
$249
Medications
semaglutidetirzepatide
Pros
- ✓The programme lives on as WeightWatchers Clinic, which is reviewed separately on this site
- ✓Its original model - GLP-1 medication paired with registered dietitian support and behaviour change - carried over into the WeightWatchers offering
- ✓Members transitioned into a larger organisation with an established insurance and coverage operation
Cons
- ✗You cannot sign up for Sequence. It no longer exists as a standalone service and both former domains are offline - go to WeightWatchers Clinic instead
- ✗Historic pricing and plan details from the Sequence era no longer apply, so any figures you find elsewhere for it are out of date
- ✗Because the brand was absorbed, older reviews and testimonials for Sequence describe a service that has since changed hands and structure
Feature-by-feature comparison
| Feature | Enhance MD | Sequence (now WeightWatchers Clinic) |
|---|---|---|
| Monthly Price | $212 | $249 |
| Rating | 7.7/10 | 7.5/10 |
| Medications | semaglutide, tirzepatide | semaglutide, tirzepatide |
| Insurance Accepted | No | Yes |
| Support Hours | Not published | Not applicable |
| Live Chat | No | No |
| Free Shipping | Yes | No |
| Shipping Speed | Medication shipped every 12 weeks | Not applicable - service discontinued |
| Mobile App | No | No |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | Ongoing provider care and support included | Not applicable - service discontinued |
| Money-back Guarantee | Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding | Not applicable |
| Cancellation Policy | Plans run monthly or in 3+ month blocks; no separate cancellation policy published | Not applicable - service discontinued |
Which should you choose?
Choose Enhance MD if you:
- →Want to save $37/month with a more affordable option
- →Prefer a higher-rated service (7.7/10 vs 7.5/10)
- →Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill
Choose Sequence (now WeightWatchers Clinic) if you:
- →Need insurance coverage for your treatment
- →Want personalized coaching support included
- →Value: the programme lives on as weightwatchers clinic, which is reviewed separately on this site
Website previews
Enhance MD
Sequence (now WeightWatchers Clinic)
Our recommendation
Enhance MD comes out ahead with a higher rating of 7.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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