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Enhance MD vs SkinnyRx

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Enhance MD vs SkinnyRx: Overview

Choosing between Enhance MD and SkinnyRx for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Enhance MD offers both semaglutide and tirzepatide at $212/month with a rating of 7.7/10. SkinnyRx also provides both semaglutide and tirzepatide at $199/month with a 8/10 rating.

With only a $13/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$13/mo

Rating Difference

0.3

Winner

SkinnyRx

Best For

Budget

Enhance MD

View full Enhance MD review →

Rating

7.7/10

Monthly Price

$212

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

SkinnyRx

View full SkinnyRx review →

Rating

8/10Better

Monthly Price

$199Cheaper

Medications

semaglutidetirzepatide

Pros

✓Trustpilot rating of 4.8 across 5,272 reviews, an unusually strong independent signal for this category
✓Publishes a customer phone number, +1 (888) 979-9580, and a support email rather than hiding behind a portal
✓Full refund available any time before a licensed provider completes your prescription
✓Compounded injectable semaglutide from $199/month and tirzepatide, as tablets or injection, from $299/month, with microdose options (checked July 26, 2026)
✓Carefully separates compounded from brand-name in its own disclosures instead of implying the two are the same
✓Buy-now-pay-later through Affirm with the APR disclosed openly - the site gives a worked example of $800 split into 12 payments of $72.21 at 15% APR
✓A mobile app for meal plans, medication tracking and weight logging, plus unlimited provider messaging and free shipping
✓A substantial clinical content library covering practical issues like GLP-1s with levothyroxine, gallbladder pain and surgery timing

Cons

✗A '90-day money-back guarantee' is advertised in a banner on every page, but the site's own /money-back-guarantee link returns a 404 reading 'Page not found... Probably the link is broken'. We could not find the terms of that guarantee anywhere
✗The hero promises 'FDA-approved Wegovy, Foundayo and other GLP-1s', yet both the Wegovy Pill and Foundayo Pill are marked 'Unavailable' in the product list directly below
✗Pricing is at the higher end for compounded product: $199/month for semaglutide and $299/month for tirzepatide, where several rivals advertise under $150
✗'Lose up to 14.9% of your body weight' takes the figure from the STEP 1 trial of branded semaglutide and applies it to a compounded preparation that has not been trialled
✗The published refund window closes as soon as a provider completes your prescription, which can be the same day you sign up
✗A pop-up offers 'up to 43% off' without stating what plan or commitment unlocks that discount
✗No BBB profile or complaint history to cross-check the Trustpilot score against
✗No published support hours, so the phone line's availability is unknown

Choose SkinnyRx

Feature-by-feature comparison

Feature	Enhance MD	SkinnyRx
Monthly Price	$212	$199
Rating	7.7/10	8/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Medication shipped every 12 weeks	Not published
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing provider care and support included	Unlimited provider messaging plus app-based tracking
Money-back Guarantee	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding	A 90-day money-back guarantee is advertised sitewide, but its terms page returns a 404; a full refund is available before a provider completes your prescription
Cancellation Policy	Plans run monthly or in 3+ month blocks; no separate cancellation policy published	Cancel anytime; full refund only before the prescription is completed by a provider

Which should you choose?

Choose Enhance MD if you:

→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Choose SkinnyRx if you:

→Want to save $13/month with a more affordable option
→Prefer a higher-rated service (8/10 vs 7.7/10)
→Value: trustpilot rating of 4.8 across 5,272 reviews, an unusually strong independent signal for this category

Get started with SkinnyRx

Website previews

Enhance MD

Enhance MD website

SkinnyRx

SkinnyRx website

Our recommendation

SkinnyRx comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with SkinnyRx

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