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Enhance MD vs TrimRx

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Enhance MD vs TrimRx: Overview

Choosing between Enhance MD and TrimRx for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Enhance MD offers both semaglutide and tirzepatide at $212/month with a rating of 7.7/10. TrimRx also provides both semaglutide and tirzepatide at $199/month with a 7.4/10 rating.

With only a $13/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$13/mo

Rating Difference

0.3

Winner

Enhance MD

Best For

Quality

Enhance MD

View full Enhance MD review →

Rating

7.7/10Better

Monthly Price

$212

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

TrimRx

View full TrimRx review →

Rating

7.4/10

Monthly Price

$199Cheaper

Medications

semaglutidetirzepatide

Pros

✓Published tier pricing you can read before you sign up: compounded GLP-1 at $174/mo month-to-month, $166 (3-month), $158 (6-month) or $149 (12-month); GLP-1 + GIP at $279, $266, $258 and $249 (checked July 26, 2026)
✓Same price at every dose, so your cost does not climb as you titrate up
✓The monthly fee bundles the telehealth visit, the medication, shipping and ongoing support - there is no separate consultation charge
✓Free 2-day shipping, and the terms commit to dispatch within 48 business hours of prescription approval
✓Unusually candid legal terms: TrimRx states in writing that compounded medications are not FDA-approved and makes no claim they are equivalent to the branded drugs
✓Providers will also write prescriptions for FDA-approved Ozempic ($1,299/mo) or Zepbound ($1,399/mo), fulfilled on a limited basis
✓BBB accredited since June 2025 and a LegitScript seal on site, with a real San Diego business address and published phone number
✓Available in all 50 states, with no insurance required

Cons

✗The advertised price is not the ongoing price. The terms list the GLP-1 follow-up month at $299 and GLP-1 + GIP at $399, while landing pages headline $149-$174. Those low rates require paying 3 to 12 months upfront
✗The 'lose weight or your money back' guarantee is contradicted twice over: the same landing page's disclaimer says weight loss is not guaranteed, and the refund policy allows refunds only for medical disqualification or a TrimRx billing error
✗Refund requests must be emailed within 28 days of payment; anything later, or sent through another channel, 'will not be honored'. Once your intake is submitted the order is non-refundable
✗The terms describe the opening offer as 'originally priced at $179, currently offered at $199' - the discounted price is higher than the original
✗Headline results (18% average weight loss, 93% 'kept the weight off for good', 6x more than diet and exercise) are footnoted as TrimRx's own patient data over six months, are not published anywhere, and cannot support a claim about keeping weight off permanently
✗Patient counts on a single page range from '10,000+' to 'over 100,000' to '350,000+'
✗The landing page shows a '4.9 Excellent Rating' in five gold stars with no source attached. The one public review platform we could find, Trustpilot, has TrimRx at 3.6 out of 5
✗Urgency devices throughout: a countdown timer, 'Only 9 Spots Left!', and a rotating stack of discounts ($120, $140, $200) that differs by landing page
✗One live funnel still carries a different brand's name ('THE TRINITYMEDS DIFFERENCE'), and the weight-loss calculator renders the placeholder text 'Missing variables: users'
✗No published clinician licence numbers, no live chat, and no insurance billing

Feature-by-feature comparison

Feature	Enhance MD	TrimRx
Monthly Price	$212	$199
Rating	7.7/10	7.4/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	24/7 support claimed
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Medication shipped every 12 weeks	Ships within 48 business hours, 1-2 day delivery claimed
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing provider care and support included	Unlimited messaging and appointments claimed
Money-back Guarantee	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding	Advertised as lose weight or your money back, but the terms allow refunds only for medical disqualification or a billing error, requested in writing within 28 days
Cancellation Policy	Plans run monthly or in 3+ month blocks; no separate cancellation policy published	Cancel anytime to stop future charges; processed charges are not refunded and orders are final once your intake is submitted

Which should you choose?

Choose Enhance MD if you:

→Prefer a higher-rated service (7.7/10 vs 7.4/10)
→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Choose TrimRx if you:

→Want to save $13/month with a more affordable option
→Value: published tier pricing you can read before you sign up: compounded glp-1 at $174/mo month-to-month, $166 (3-month), $158 (6-month) or $149 (12-month); glp-1 + gip at $279, $266, $258 and $249 (checked july 26, 2026)

Get started with TrimRx

Website previews

Enhance MD

Enhance MD website

TrimRx

TrimRx website

Our recommendation

Enhance MD comes out ahead with a higher rating of 7.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Enhance MD

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