Enhance MD vs US Scripts MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Enhance MD vs US Scripts MD: Overview

Choosing between Enhance MD and US Scripts MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Enhance MD offers both semaglutide and tirzepatide at $212/month with a rating of 7.7/10. US Scripts MD also provides both semaglutide and tirzepatide at $299/month with a 7/10 rating.

The price difference of $87/month is significant - Enhance MD is the more budget-friendly option, while US Scripts MD positions itself as a premium service.

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Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$87/mo
Rating Difference
0.7
Winner
Enhance MD
Best For
Budget

Enhance MD

View full Enhance MD review →
Rating
7.7/10Better
Monthly Price
$212Cheaper
Medications
semaglutidetirzepatide

Pros

  • One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
  • Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
  • The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
  • Product images are labelled 'Not actual vial - For marketing purposes only'
  • The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
  • Medication ships quarterly, so there are fewer delivery events to manage
  • Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

  • Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
  • The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
  • First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
  • Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
  • This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
  • No published customer phone number or support hours
  • No BBB profile or independent complaint record to check
  • Quarterly shipping means committing to a longer supply of a medication you may not tolerate
Choose Enhance MD

US Scripts MD

View full US Scripts MD review →
Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide

Pros

  • One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
  • No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
  • Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
  • Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
  • An injection kit with spare syringes is included in every shipment
  • Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
  • 24/7 access to board-certified doctor support is advertised
  • You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
  • A $100 discount on the first month of weight-loss treatment

Cons

  • Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
  • The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
  • Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
  • The medication is compounded and not FDA-approved
  • The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
  • The dispensing pharmacy is not named
  • No insurance billing, and HSA/FSA acceptance is not stated
  • No published phone number
Choose US Scripts MD

Feature-by-feature comparison

FeatureEnhance MDUS Scripts MD
Monthly Price$212$299
Rating7.7/107/10
Medicationssemaglutide, tirzepatideliraglutide, semaglutide
Insurance AcceptedNoNo
Support HoursNot publishedCompany advertises 24/7 access to partnering board-certified doctors
Live ChatNoNo
Free ShippingYesYes
Shipping SpeedMedication shipped every 12 weeksFree overnight shipping in temperature-controlled packaging
Mobile AppNoNo
Dedicated CoachNot includedNot included
Follow-up FrequencyOngoing provider care and support included24/7 access to partnering board-certified doctors for questions and support
Money-back GuaranteeAdvertised as a 100% money-back guarantee, but it only covers being found ineligible during onboardingFull refund if the medical providers determine you are not a fit for the programme
Cancellation PolicyPlans run monthly or in 3+ month blocks; no separate cancellation policy publishedCancel any time before your order ships; no contracts

Which should you choose?

Choose Enhance MD if you:

  • Want to save $87/month with a more affordable option
  • Prefer a higher-rated service (7.7/10 vs 7/10)
  • Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Choose US Scripts MD if you:

  • Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1

Website previews

Enhance MD

Enhance MD website

US Scripts MD

US Scripts MD website

Our recommendation

Enhance MD comes out ahead with a higher rating of 7.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with Enhance MD

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