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LifeMD vs RxSpan MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

LifeMD vs RxSpan MD: Overview

Choosing between LifeMD and RxSpan MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

LifeMD offers both semaglutide and tirzepatide at $199/month with a rating of 8.5/10. RxSpan MD also provides both semaglutide and tirzepatide at $249/month with a 7.6/10 rating.

With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$50/mo

Rating Difference

0.9

Winner

LifeMD

Best For

Budget

LifeMD

View full LifeMD review →

Rating

8.5/10Better

Monthly Price

$199Cheaper

Medications

semaglutidetirzepatide

Pros

✓Prescribes FDA-approved branded GLP-1s - Zepbound and Wegovy - rather than compounded preparations, so you get the exact product the trials studied
✓Accepts insurance including Medicare, and advertises as low as $0 copay for branded GLP-1s where coverage applies
✓Publishes cash prices too: Wegovy Pen from $199/month and Zepbound Vial from $349/month (checked July 28, 2026)
✓Offers an outcome-based guarantee: 'lose 10% of your weight or your money back', which ties the promise to a result rather than a satisfaction survey
✓HSA and FSA eligible
✓Weight care sits inside a full telehealth service, so urgent care, labs and other specialties are available under the same account

Cons

✗The rotating banner on the weight-management page shows the Wegovy Pen at both '$199' and '$499' in the same carousel, which makes the real starting price unclear before you sign up
✗The money-back guarantee carries a footnote marker on site, so read the qualifying conditions before relying on it
✗Insurance coverage for obesity medication is patchy, so the '$0 copay' outcome will not apply to many people and the cash prices are what you should plan around
✗A 4.0 Trustpilot average is mid-range for this category
✗Branded GLP-1s at $199-$349/month are more expensive than compounded alternatives, which is the trade-off for using an FDA-approved product
✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy

RxSpan MD

View full RxSpan MD review →

Rating

7.6/10

Monthly Price

$249

Medications

semaglutidetirzepatide

Pros

✓A full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked July 27, 2026)
✓Brand-name options are offered and priced openly too - Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069
✓The plan ladder is shown with each rate: $249/mo monthly, $219/mo on 3 months, $199/mo on 6 months and $194/mo on 12 months
✓The price is stated to include the consult, medication, supplies, shipping and support, with no separate membership fee
✓Oral capsule versions of both semaglutide and tirzepatide are available for people who do not want injections
✓Plans can be cancelled or changed at any time
✓The site states plainly that 'Prescription is not guaranteed' rather than implying approval is automatic
✓A named, credentialled physician is associated with the service rather than an anonymous 'medical team'

Cons

✗Every headline price is labelled 'For the first month'. What you pay from month two is not shown anywhere on the product screen, so the ongoing cost is unknown until you are further into the funnel
✗You pay at checkout before a provider reviews your case - the site confirms 'After checkout, a provider will review your information to determine if treatment is right for you' - so your money goes first and eligibility is decided afterwards
✗There is no independent review signal at all: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Brand-name pricing is far above the manufacturers' own direct-pay programmes - $1,349 for Wegovy and $1,069 for Zepbound against considerably cheaper NovoCare and LillyDirect routes
✗No customer phone number is published; the only contact is an email address
✗The supervising physician's board certification is in plastic surgery, not obesity medicine, endocrinology or internal medicine
✗The banner copy - 'No Hidden Fees', 'Free, Expedited Delivery', 'Doctor-led Plans & Coaching' - is word-for-word identical to TrimRx's, indicating a shared white-label funnel rather than an independently built service
✗Product prices only render once JavaScript loads; with scripts blocked the weight-loss category reads 'No products found for Weight Loss'

Choose RxSpan MD

Feature-by-feature comparison

Feature	LifeMD	RxSpan MD
Monthly Price	$199	$249
Rating	8.5/10	7.6/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	Yes	No
Support Hours	Mon-Fri 8AM-8PM ET	Not published
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	3-5 days	Free expedited delivery claimed; timeframe not published
Mobile App	Available	No
Dedicated Coach	Not included	Included
Follow-up Frequency	Quarterly	Doctor-led plans and coaching advertised; frequency not published
Money-back Guarantee	Lose 10% of your weight or your money back (conditions apply)	None published; you are charged at checkout before a provider decides whether to prescribe
Cancellation Policy	Cancel anytime	Cancel or change plans at any time

Which should you choose?

Choose LifeMD if you:

→Want to save $50/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 7.6/10)
→Need insurance coverage for your treatment
→Value: prescribes fda-approved branded glp-1s - zepbound and wegovy - rather than compounded preparations, so you get the exact product the trials studied

Get started with LifeMD

Choose RxSpan MD if you:

→Want personalized coaching support included
→Value: a full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked july 27, 2026)

Get started with RxSpan MD

Website previews

LifeMD

LifeMD website

RxSpan MD

RxSpan MD website

Our recommendation

LifeMD comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with LifeMD

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