← All providers

MangoRx vs Brightmeds

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

MangoRx vs Brightmeds: Overview

Choosing between MangoRx and Brightmeds for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

MangoRx offers both semaglutide and tirzepatide at $299/month with a rating of 7.4/10. Brightmeds also provides both semaglutide and tirzepatide at $289/month with a 8.2/10 rating.

With only a $10/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$10/mo

Rating Difference

0.8

Winner

Brightmeds

Best For

Budget

MangoRx

View full MangoRx review →

Rating

7.4/10

Monthly Price

$299

Medications

oral semaglutidetestosteronesildenafiltadalafil

Pros

✓Pricing is published without an intake and stated as locked in with no hidden fees: Slim oral semaglutide at $299/month and TRT starting at $99/month (checked July 28, 2026)
✓Provider visits and shipping are free on all orders, so there is no separate consultation fee stacked on top
✓The TRT program includes a comprehensive lab test and a personalized plan, with a full refund if you do not qualify - so the assessment carries no financial risk
✓The compounded-medication disclosure is thorough and correctly worded, including the point that clinical data from FDA-approved drugs may not transfer to compounded versions
✓It explicitly disclaims any relationship with Novo Nordisk or Eli Lilly rather than trading on their brand names
✓An orally dissolving tablet is a genuine convenience for people who will not inject, and the formulation adds vitamin B6, which the site says is intended to reduce nausea
✓Replied to 100% of negative Trustpilot reviews
✓A dedicated safety page, pharmacy disclaimer and telehealth consent are all published and dated

Cons

✗At $299/month, Slim is one of the more expensive semaglutide options we cover - and it is compounded. For comparison, the FDA-approved oral semaglutide listed elsewhere on this site sits at $149/month, so you would be paying roughly double for a preparation the FDA has not reviewed
✗There is no published bioavailability data for this tablet. Approved oral semaglutide relies on an absorption enhancer (SNAC) plus a strict fasting-and-water protocol precisely because semaglutide is a peptide that is poorly absorbed by mouth. Without that data, there is no way to know how much drug a compounded orally dissolving tablet actually delivers
✗The weight-loss figures associated with semaglutide - roughly 14.9% of body weight over 68 weeks in the STEP-1 trial - come from weekly subcutaneous injections of the branded drug, not from a compounded oral tablet. Do not assume the results transfer
✗The FDA declared the semaglutide shortage resolved in early 2025, after which compounders were required to stop producing what amounts to a copy of an approved drug. Providers still selling compounded semaglutide generally argue their formulation is materially different. It is a fair question to put to the provider before paying
✗The refund policy covers dispensing errors, cancellation before filling, and shipping damage reported within 7 days. It does not cover simply not getting on with the treatment
✗Only 15 Trustpilot reviews, and no BBB profile, so there is very little independent evidence either way
✗No corporate entity, address or phone number appears anywhere on the site - support is a single email address
✗This offer is not available in Alabama, Alaska, Arkansas, California, Kentucky, Louisiana, Michigan, Mississippi, North Dakota, South Carolina, South Dakota or Wyoming
✗The brand voice leans heavily on bravado - 'MAN. GO.', 'You badass' - which sits oddly against prescribing a GLP-1 and testosterone, where the tone you want is clinical caution
✗Semaglutide is not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, and is not for use in pregnancy. Pancreatitis and gallbladder disease are recognised risks

Brightmeds

View full Brightmeds review →

Rating

8.2/10Better

Monthly Price

$289Cheaper

Medications

semaglutidetirzepatide

Pros

✓Offers FDA-approved Zepbound pens and vials alongside its compounded range, so the branded route is available without leaving the platform
✓The compounded disclosure names both 503A and 503B pathways and explains why compounded drugs are not FDA-approved, rather than reciting boilerplate
✓Trademark ownership is acknowledged explicitly - Zepbound and Mounjaro attributed to Eli Lilly - instead of presenting compounds as the brands
✓Same price regardless of prescribed dose, so titrating up does not raise the bill
✓Microdosing versions of both semaglutide and tirzepatide are offered for people wanting a lower-intensity option
✓A full refund is given if you are not approved for treatment
✓Trustpilot rating of 4.8 across 906 reviews
✓Treatments are prescribed and monitored by board-certified US-licensed physicians, and the price includes medication, the online consult and ongoing support

Cons

✗The semaglutide page quotes two different starting prices in the same view: 'Get started for $183' in one block and 'Starting at $189/first month' in another, with no explanation of the difference
✗The introductory price rises sharply at renewal - $189 for the first month becomes $289/month thereafter, so the headline is a first-month figure rather than what you will pay ongoing
✗The affiliate link for this offer lands on Brightmeds' sermorelin funnel rather than its GLP-1 pages, so anyone following it for weight loss arrives at a growth-hormone peptide product
✗Basic copy errors appear on the purchase page, including '$289/mo therafter' and 'Save $50 on our First Order'
✗A 'Weight Loss Guarantee' is linked in the footer but its terms are not surfaced anywhere on the product pages
✗No BBB profile or complaint history exists to set against the Trustpilot score
✗No published customer phone number or support hours
✗As with all compounded GLP-1s, the products have not been evaluated by the FDA for safety, efficacy or quality - Brightmeds says so clearly, but it remains the core caveat

Choose Brightmeds

Feature-by-feature comparison

Feature	MangoRx	Brightmeds
Monthly Price	$299	$289
Rating	7.4/10	8.2/10
Medications	oral semaglutide, testosterone, sildenafil, tadalafil	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free discreet shipping on all orders; Slim ships monthly as a 30-day supply	Shipped to your door; timeframe not published
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Doctor-managed plans with lab-based adjustment on TRT; cadence not published	Ongoing support from the care team with physician monitoring
Money-back Guarantee	Full refund on TRT if you do not qualify. Otherwise refunds are limited to dispensing errors, pre-fill cancellation, or shipping damage reported within 7 days	Full refund if you are not approved for treatment; a separate 'Weight Loss Guarantee' is linked but its terms are not published
Cancellation Policy	Monthly supply; cancellation before a prescription is filled is refundable, subject to the cancellation policy	Not published on the product pages

Which should you choose?

Choose MangoRx if you:

→Want more medication options to choose from
→Value: pricing is published without an intake and stated as locked in with no hidden fees: slim oral semaglutide at $299/month and trt starting at $99/month (checked july 28, 2026)

Get started with MangoRx

Choose Brightmeds if you:

→Want to save $10/month with a more affordable option
→Prefer a higher-rated service (8.2/10 vs 7.4/10)
→Value: offers fda-approved zepbound pens and vials alongside its compounded range, so the branded route is available without leaving the platform

Get started with Brightmeds

Website previews

MangoRx

MangoRx website

Brightmeds

Brightmeds website

Our recommendation

Brightmeds comes out ahead with a higher rating of 8.2/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Brightmeds

Related comparisons

MangoRx vs CoreAge Rx

MangoRx vs Zepbound

MangoRx vs Mounjaro

MangoRx vs Wegovy Pill

MangoRx vs Foundayo

MangoRx vs Wegovy

MangoRx vs NovoCare Pharmacy

MangoRx vs Ozempic

MangoRx vs Form Health

MangoRx vs Henry Meds

MangoRx vs Sesame Care

MangoRx vs FuturHealth

MangoRx vs Circle Medical

MangoRx vs Ro

MangoRx vs Midi Health

MangoRx vs Noom Med

MangoRx vs Precision Telemed

MangoRx vs Hims

MangoRx vs Calibrate

MangoRx vs PlushCare

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand