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MangoRx vs MEDVi Quad

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

MangoRx vs MEDVi Quad: Overview

Choosing between MangoRx and MEDVi Quad for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

MangoRx offers both semaglutide and tirzepatide at $299/month with a rating of 7.4/10. MEDVi Quad also provides both semaglutide and tirzepatide at $114/month with a 6.5/10 rating.

The price difference of $185/month is significant - MEDVi Quad is the more budget-friendly option, while MangoRx positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$185/mo

Rating Difference

0.9

Winner

MangoRx

Best For

Quality

MangoRx

View full MangoRx review →

Rating

7.4/10Better

Monthly Price

$299

Medications

oral semaglutidetestosteronesildenafiltadalafil

Pros

✓Pricing is published without an intake and stated as locked in with no hidden fees: Slim oral semaglutide at $299/month and TRT starting at $99/month (checked July 28, 2026)
✓Provider visits and shipping are free on all orders, so there is no separate consultation fee stacked on top
✓The TRT program includes a comprehensive lab test and a personalized plan, with a full refund if you do not qualify - so the assessment carries no financial risk
✓The compounded-medication disclosure is thorough and correctly worded, including the point that clinical data from FDA-approved drugs may not transfer to compounded versions
✓It explicitly disclaims any relationship with Novo Nordisk or Eli Lilly rather than trading on their brand names
✓An orally dissolving tablet is a genuine convenience for people who will not inject, and the formulation adds vitamin B6, which the site says is intended to reduce nausea
✓Replied to 100% of negative Trustpilot reviews
✓A dedicated safety page, pharmacy disclaimer and telehealth consent are all published and dated

Cons

✗At $299/month, Slim is one of the more expensive semaglutide options we cover - and it is compounded. For comparison, the FDA-approved oral semaglutide listed elsewhere on this site sits at $149/month, so you would be paying roughly double for a preparation the FDA has not reviewed
✗There is no published bioavailability data for this tablet. Approved oral semaglutide relies on an absorption enhancer (SNAC) plus a strict fasting-and-water protocol precisely because semaglutide is a peptide that is poorly absorbed by mouth. Without that data, there is no way to know how much drug a compounded orally dissolving tablet actually delivers
✗The weight-loss figures associated with semaglutide - roughly 14.9% of body weight over 68 weeks in the STEP-1 trial - come from weekly subcutaneous injections of the branded drug, not from a compounded oral tablet. Do not assume the results transfer
✗The FDA declared the semaglutide shortage resolved in early 2025, after which compounders were required to stop producing what amounts to a copy of an approved drug. Providers still selling compounded semaglutide generally argue their formulation is materially different. It is a fair question to put to the provider before paying
✗The refund policy covers dispensing errors, cancellation before filling, and shipping damage reported within 7 days. It does not cover simply not getting on with the treatment
✗Only 15 Trustpilot reviews, and no BBB profile, so there is very little independent evidence either way
✗No corporate entity, address or phone number appears anywhere on the site - support is a single email address
✗This offer is not available in Alabama, Alaska, Arkansas, California, Kentucky, Louisiana, Michigan, Mississippi, North Dakota, South Carolina, South Dakota or Wyoming
✗The brand voice leans heavily on bravado - 'MAN. GO.', 'You badass' - which sits oddly against prescribing a GLP-1 and testosterone, where the tone you want is clinical caution
✗Semaglutide is not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, and is not for use in pregnancy. Pancreatitis and gallbladder disease are recognised risks

MEDVi Quad

View full MEDVi Quad review →

Rating

6.5/10

Monthly Price

$114Cheaper

Medications

sildenafiltadalafilbremelanotide (PT-141)L-citrulline

Pros

✓$114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked July 28, 2026)
✓Cancel anytime, and the page states you are not charged if you do not qualify
✓All four active ingredients are named openly - PT-141 (bremelanotide), L-citrulline, sildenafil and tadalafil - rather than hidden behind a proprietary blend name
✓Sublingual delivery is a real advantage over tablets: it bypasses first-pass metabolism, so onset is faster and a heavy meal does not blunt absorption the way it can with oral sildenafil
✓Backed by a substantial independent review record - roughly 14,000 Trustpilot reviews at 4.4, with 99% of negative reviews answered
✓A published phone number, email address and physical address, which many competitors in this category omit entirely

Cons

✗'Peak rigidity guaranteed' appears directly in the product copy. No prescription medication can guarantee an outcome, and this is the most explicit outcome promise we have seen across every provider reviewed on this site
✗The formula stacks two PDE5 inhibitors - sildenafil and tadalafil - and then adds L-citrulline, a nitric oxide precursor. All three act on the same nitric oxide and cGMP pathway, so the blood-pressure-lowering effect compounds three ways rather than one
✗PT-141 adds a fourth agent that independently causes low blood pressure, nausea and flushing. Four actives, four routes to hypotension, and no discussion anywhere on the page of the combined risk
✗Bremelanotide's only FDA approval is as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Prescribing it to men in a compounded sublingual liquid is off-label and a different route of administration
✗The word FDA does not appear on the page at all. The product is compounded, and the page never states the consequence - that compounded preparations are not reviewed or approved by the FDA for safety, efficacy or quality
✗'The world's first 4-in-1 formula' and 'hospital-grade power' are unverifiable marketing superlatives attached to a prescription product
✗The advertised Trustpilot score covers MEDVi's business as a whole rather than this specific product
✗The published address is a suite at a Delaware registered-agent building, not a clinical facility
✗Anyone taking nitrates or riociguat must not use this product. The PT-141 component also interacts with 5-HT3 anti-emetics such as ondansetron, and stacking two PDE5 inhibitors makes the nitrate contraindication more dangerous, not less

Choose MEDVi Quad

Feature-by-feature comparison

Feature	MangoRx	MEDVi Quad
Monthly Price	$299	$114
Rating	7.4/10	6.5/10
Medications	oral semaglutide, testosterone, sildenafil, tadalafil	sildenafil, tadalafil, bremelanotide (PT-141), L-citrulline
Insurance Accepted	No	No
Support Hours	Not published	24/7 medical support advertised
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free discreet shipping on all orders; Slim ships monthly as a 30-day supply	Free rush shipping included in the monthly price
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Doctor-managed plans with lab-based adjustment on TRT; cadence not published	24/7 medical support advertised; follow-up cadence not published
Money-back Guarantee	Full refund on TRT if you do not qualify. Otherwise refunds are limited to dispensing errors, pre-fill cancellation, or shipping damage reported within 7 days	No charge if you do not qualify; no refund policy published for dispensed medication
Cancellation Policy	Monthly supply; cancellation before a prescription is filled is refundable, subject to the cancellation policy	Cancel anytime

Which should you choose?

Choose MangoRx if you:

→Prefer a higher-rated service (7.4/10 vs 6.5/10)
→Value: pricing is published without an intake and stated as locked in with no hidden fees: slim oral semaglutide at $299/month and trt starting at $99/month (checked july 28, 2026)

Get started with MangoRx

Choose MEDVi Quad if you:

→Want to save $185/month with a more affordable option
→Value: $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked july 28, 2026)

Get started with MEDVi Quad

Website previews

MangoRx

MangoRx website

MEDVi Quad

MEDVi Quad website

Our recommendation

MangoRx comes out ahead with a higher rating of 7.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with MangoRx

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