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MangoRx vs TMates

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

MangoRx vs TMates: Overview

Choosing between MangoRx and TMates for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

MangoRx offers both semaglutide and tirzepatide at $299/month with a rating of 7.4/10. TMates also provides both semaglutide and tirzepatide at $249/month with a 7.8/10 rating.

With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$50/mo

Rating Difference

0.4

Winner

TMates

Best For

Budget

MangoRx

View full MangoRx review →

Rating

7.4/10

Monthly Price

$299

Medications

oral semaglutidetestosteronesildenafiltadalafil

Pros

✓Pricing is published without an intake and stated as locked in with no hidden fees: Slim oral semaglutide at $299/month and TRT starting at $99/month (checked July 28, 2026)
✓Provider visits and shipping are free on all orders, so there is no separate consultation fee stacked on top
✓The TRT program includes a comprehensive lab test and a personalized plan, with a full refund if you do not qualify - so the assessment carries no financial risk
✓The compounded-medication disclosure is thorough and correctly worded, including the point that clinical data from FDA-approved drugs may not transfer to compounded versions
✓It explicitly disclaims any relationship with Novo Nordisk or Eli Lilly rather than trading on their brand names
✓An orally dissolving tablet is a genuine convenience for people who will not inject, and the formulation adds vitamin B6, which the site says is intended to reduce nausea
✓Replied to 100% of negative Trustpilot reviews
✓A dedicated safety page, pharmacy disclaimer and telehealth consent are all published and dated

Cons

✗At $299/month, Slim is one of the more expensive semaglutide options we cover - and it is compounded. For comparison, the FDA-approved oral semaglutide listed elsewhere on this site sits at $149/month, so you would be paying roughly double for a preparation the FDA has not reviewed
✗There is no published bioavailability data for this tablet. Approved oral semaglutide relies on an absorption enhancer (SNAC) plus a strict fasting-and-water protocol precisely because semaglutide is a peptide that is poorly absorbed by mouth. Without that data, there is no way to know how much drug a compounded orally dissolving tablet actually delivers
✗The weight-loss figures associated with semaglutide - roughly 14.9% of body weight over 68 weeks in the STEP-1 trial - come from weekly subcutaneous injections of the branded drug, not from a compounded oral tablet. Do not assume the results transfer
✗The FDA declared the semaglutide shortage resolved in early 2025, after which compounders were required to stop producing what amounts to a copy of an approved drug. Providers still selling compounded semaglutide generally argue their formulation is materially different. It is a fair question to put to the provider before paying
✗The refund policy covers dispensing errors, cancellation before filling, and shipping damage reported within 7 days. It does not cover simply not getting on with the treatment
✗Only 15 Trustpilot reviews, and no BBB profile, so there is very little independent evidence either way
✗No corporate entity, address or phone number appears anywhere on the site - support is a single email address
✗This offer is not available in Alabama, Alaska, Arkansas, California, Kentucky, Louisiana, Michigan, Mississippi, North Dakota, South Carolina, South Dakota or Wyoming
✗The brand voice leans heavily on bravado - 'MAN. GO.', 'You badass' - which sits oddly against prescribing a GLP-1 and testosterone, where the tone you want is clinical caution
✗Semaglutide is not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, and is not for use in pregnancy. Pancreatitis and gallbladder disease are recognised risks

TMates

View full TMates review →

Rating

7.8/10Better

Monthly Price

$249Cheaper

Medications

semaglutidetirzepatide

Pros

✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
✓Both injectable and oral formats are offered at the same published prices
✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms

Cons

✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
✗No published customer phone number, support email or support hours
✗No BBB profile or complaint record to check

Feature-by-feature comparison

Feature	MangoRx	TMates
Monthly Price	$299	$249
Rating	7.4/10	7.8/10
Medications	oral semaglutide, testosterone, sildenafil, tadalafil	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free discreet shipping on all orders; Slim ships monthly as a 30-day supply	Free shipping; timeframe not published
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Doctor-managed plans with lab-based adjustment on TRT; cadence not published	Ongoing provider support included
Money-back Guarantee	Full refund on TRT if you do not qualify. Otherwise refunds are limited to dispensing errors, pre-fill cancellation, or shipping damage reported within 7 days	None published
Cancellation Policy	Monthly supply; cancellation before a prescription is filled is refundable, subject to the cancellation policy	Cancel anytime, but multi-month plans are paid upfront

Which should you choose?

Choose MangoRx if you:

→Want more medication options to choose from
→Value: pricing is published without an intake and stated as locked in with no hidden fees: slim oral semaglutide at $299/month and trt starting at $99/month (checked july 28, 2026)

Get started with MangoRx

Choose TMates if you:

→Want to save $50/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 7.4/10)
→Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026

Get started with TMates

Website previews

MangoRx

MangoRx website

TMates

TMates website

Our recommendation

TMates comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with TMates

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