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Midi Health vs System Labs

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Midi Health vs System Labs: Overview

Choosing between Midi Health and System Labs for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Midi Health offers both semaglutide and tirzepatide at $164/month with a rating of 8.6/10. System Labs also provides both semaglutide and tirzepatide at $149/month with a 6.5/10 rating.

With only a $15/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$15/mo

Rating Difference

2.1

Winner

Midi Health

Best For

Quality

Midi Health

View full Midi Health review →

Rating

8.6/10Better

Monthly Price

$164

Medications

compounded GLP-1compounded GLP-1/GIPbrand-name GLP-1s

Pros

✓The GLP-1 pricing page is the most transparent we have seen anywhere in this category: a dose-by-dose table for four different products, with shipping and supplies included in every figure (checked July 28, 2026)
✓Compounded GLP-1 injectable runs $165.90 for the lowest doses, $270.90 in the mid range and $355.00 at the top; the dual-action GLP-1/GIP injectable runs $210.00 to $434.00, all for a 4-week supply
✓Sublingual options are offered as well, from $164.00 for GLP-1 and $209.00 for dual-action GLP-1/GIP, for people who will not inject
✓Its partner compounding pharmacies are 503B-accredited. 503B outsourcing facilities register with the FDA, are subject to current good manufacturing practice requirements and are FDA-inspected - a materially higher standard than the 503A pharmacies most competitors use
✓There is no membership fee. You pay for care and medication only
✓Visits are insurance-covered for qualifying patients, and HSA/FSA funds can be used for copays and services
✓Midi will also prescribe brand-name GLP-1s sent to a pharmacy of your choice, so you are not locked into compounded product if you would rather have the approved drug
✓The efficacy claim is the best-sourced in this category. Midi reports patients lost an average of 16 lbs after six or more months, and footnotes it to a retrospective analysis of 6,958 patients who completed two or more weight management visits between 1 May 2025 and 30 April 2026, while stating plainly that weight data were self-reported and results are not guaranteed
✓Care is genuinely whole-person for midlife women - perimenopause, menopause, weight, mood and memory, sexual wellness, hair and skin, sleep, and cancer survivorship - with lab orders and lifestyle support included where appropriate
✓Available in all 50 states

Cons

✗The compounded products are still not FDA-approved. 503B accreditation raises the manufacturing standard considerably but does not mean the FDA has reviewed these preparations for safety or efficacy
✗Midi never names the active drug anywhere in its pricing. Everything is labelled 'GLP-1' or 'GLP-1/GIP'. The dose ladders shown - 0.25 through 2.5 mg, and 2.5 through 15 mg - match the standard semaglutide and tirzepatide titrations exactly, but you should confirm with the clinician what you are actually being prescribed
✗Microdosing is offered from $34 a week for eligible patients. Microdosing is not an evidence-based protocol - the trials behind these drugs used full therapeutic doses, and the 16 lb outcome figure covers patients on 'a range of treatments', not microdosing specifically
✗Medicaid and Medi-Cal patients cannot be treated at all, even if they offer to pay cash
✗Medicare does not cover Midi, and beneficiaries cannot submit claims for visits, medications or associated services
✗Prices rise steeply as you titrate up. Injectable GLP-1 more than doubles from $165.90 to $355.00, and the dual-action sublingual runs from $209.00 to $460.00, so the entry price is not what you will pay long term
✗The 16 lb average comes from self-reported weights in a retrospective chart review with no control group - well documented, but not a controlled trial
✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy. Pancreatitis and gallbladder disease are recognised risks

Choose Midi Health

System Labs

View full System Labs review →

Rating

6.5/10

Monthly Price

$149Cheaper

Medications

NAD+sermorelinglutathioneMIC + B12GHK-Cu

Pros

✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
✓Products are described as American made and third-party tested
✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
✓No insurance required and no membership fee stacked on top of the product price

Cons

✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
✗No published phone number, support hours or physical address
✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes

Choose System Labs

Feature-by-feature comparison

Feature	Midi Health	System Labs
Monthly Price	$164	$149
Rating	8.6/10	6.5/10
Medications	compounded GLP-1, compounded GLP-1/GIP, brand-name GLP-1s	NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu
Insurance Accepted	Yes	No
Support Hours	Not published	Medical team availability advertised; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Discreet shipping included in every quoted medication price	Free 2-day shipping
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Continued care visits with the same clinician, covered by insurance for qualifying patients	Ongoing clinician support advertised; frequency not published
Money-back Guarantee	None published	None published
Cancellation Policy	No membership fee and no subscription lock-in; you pay for care and medication only	Not published

Which should you choose?

Choose Midi Health if you:

→Prefer a higher-rated service (8.6/10 vs 6.5/10)
→Need insurance coverage for your treatment
→Value: the glp-1 pricing page is the most transparent we have seen anywhere in this category: a dose-by-dose table for four different products, with shipping and supplies included in every figure (checked july 28, 2026)

Get started with Midi Health

Choose System Labs if you:

→Want to save $15/month with a more affordable option
→Want more medication options to choose from
→Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)

Get started with System Labs

Website previews

Midi Health

Midi Health website

System Labs

System Labs website

Our recommendation

Midi Health comes out ahead with a higher rating of 8.6/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Midi Health

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