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PlushCare vs Amie

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

PlushCare vs Amie: Overview

Choosing between PlushCare and Amie for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. Amie also provides both semaglutide and tirzepatide at $99/month with a 6.5/10 rating.

The price difference of $79/month is significant - PlushCare is the more budget-friendly option, while Amie positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$79/mo

Rating Difference

2.0

Winner

PlushCare

Best For

Budget

PlushCare

View full PlushCare review →

Rating

8.5/10Better

Monthly Price

$20Cheaper

Medications

semaglutidetirzepatideliraglutide

Pros

✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
✓Membership is $19.99/month with the first month free, and there is no minimum commitment
✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
✓A full refund is offered if the doctor is unable to treat you
✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site

Choose PlushCare

Amie

View full Amie review →

Rating

6.5/10

Monthly Price

$99

Medications

semaglutidetirzepatide

Pros

✓Pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
✓No shipment unless a provider approves you, stated on the pricing panel
✓Optional add-ons are priced separately and openly rather than bundled in silently

Cons

✗The FDA has formally told Amie that its website misrepresented its compounded products - see the warning letter above
✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
✗The three-month rate requires paying $249 up front
✗No phone number or support hours published

Feature-by-feature comparison

Feature	PlushCare	Amie
Monthly Price	$20	$99
Rating	8.5/10	6.5/10
Medications	semaglutide, tirzepatide, liraglutide	semaglutide, tirzepatide
Insurance Accepted	Yes	No
Support Hours	Video visits available 24/7	Not published
Live Chat	No	No
Free Shipping	No	Yes
Shipping Speed	Filled at your pharmacy; not shipped by PlushCare	Not published; no shipment unless approved
Mobile App	Available	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing management with a board-certified primary care physician	Not published
Money-back Guarantee	Full refund if the doctor is unable to treat you; medication and lab costs are never included	None published
Cancellation Policy	Cancel anytime, no minimum commitment; first month of membership is free	Monthly or 3-month plans; terms not summarised on the pricing panel

Which should you choose?

Choose PlushCare if you:

→Want to save $79/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 6.5/10)
→Want more medication options to choose from
→Need insurance coverage for your treatment
→Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Get started with PlushCare

Choose Amie if you:

→Value: pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249

Get started with Amie

Website previews

PlushCare

PlushCare website

Amie

Amie website

Our recommendation

PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with PlushCare

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