PlushCare vs Calibrate

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

PlushCare vs Calibrate: Overview

Choosing between PlushCare and Calibrate for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. Calibrate also provides both semaglutide and tirzepatide at $199/month with a 8.5/10 rating.

The price difference of $179/month is significant - PlushCare is the more budget-friendly option, while Calibrate positions itself as a premium service.

VERIFIED

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$179/mo
Rating Difference
0.0
Winner
PlushCare
Best For
Budget

PlushCare

View full PlushCare review →
Rating
8.5/10
Monthly Price
$20Cheaper
Medications
semaglutidetirzepatideliraglutide

Pros

  • Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
  • Membership is $19.99/month with the first month free, and there is no minimum commitment
  • Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
  • Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
  • A full refund is offered if the doctor is unable to treat you
  • Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
  • An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
  • The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

  • The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
  • Visits are charged on top of membership - $129 for an initial visit without in-network insurance
  • Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
  • Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
  • This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
  • Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
  • Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
  • If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site
Choose PlushCare

Calibrate

View full Calibrate review →
Rating
8.5/10
Monthly Price
$199
Medications
semaglutidetirzepatide

Pros

  • Prescribes only brand-name, FDA-approved GLP-1s - Zepbound, Mounjaro, Wegovy, Ozempic and Foundayo - with no compounded products
  • Publishes a genuine long-term outcome: 20% weight loss achieved at three years, which is a far longer follow-up than the 68-72 week trial data most providers cite
  • Includes 1:1 video coaching and lifestyle support rather than shipping medication and leaving you to it
  • Dedicated insurance navigation support to get the medication covered, instead of assuming cash-pay
  • Available either directly as an individual or through a participating employer
  • Starting price is published openly at $199/month (checked July 28, 2026)

Cons

  • At $199/month for the programme, this is a coaching-led service and the medication cost is separate - what you pay in total depends on your insurance
  • The $199 figure is a 'starting at' price
  • Because it only prescribes brand-name GLP-1s, cost without insurance coverage will be substantially higher than compounded alternatives
  • The 4.5 rating from 1,618 reviews is displayed on Calibrate's own site rather than an independent platform
  • GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy
Choose Calibrate

Feature-by-feature comparison

FeaturePlushCareCalibrate
Monthly Price$20$199
Rating8.5/108.5/10
Medicationssemaglutide, tirzepatide, liraglutidesemaglutide, tirzepatide
Insurance AcceptedYesYes
Support HoursVideo visits available 24/7Not published
Live ChatNoNo
Free ShippingNoNo
Shipping SpeedFilled at your pharmacy; not shipped by PlushCarePrescriptions filled through your pharmacy
Mobile AppAvailableAvailable
Dedicated CoachNot includedIncluded
Follow-up FrequencyOngoing management with a board-certified primary care physician1:1 video coaching throughout the Metabolic Reset programme
Money-back GuaranteeFull refund if the doctor is unable to treat you; medication and lab costs are never includedNone published
Cancellation PolicyCancel anytime, no minimum commitment; first month of membership is freeProgramme based; terms not published

Which should you choose?

Choose PlushCare if you:

  • Want to save $179/month with a more affordable option
  • Want more medication options to choose from
  • Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Choose Calibrate if you:

  • Want personalized coaching support included
  • Value: prescribes only brand-name, fda-approved glp-1s - zepbound, mounjaro, wegovy, ozempic and foundayo - with no compounded products

Website previews

PlushCare

PlushCare website

Calibrate

Calibrate website

Our recommendation

PlushCare offers better value at $20/month while maintaining strong ratings. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with PlushCare

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