PlushCare vs LifeMD
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
PlushCare vs LifeMD: Overview
Choosing between PlushCare and LifeMD for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. LifeMD also provides both semaglutide and tirzepatide at $199/month with a 8.5/10 rating.
The price difference of $179/month is significant - PlushCare is the more budget-friendly option, while LifeMD positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$179/mo
Rating Difference
0.0
Winner
PlushCare
Best For
Budget
PlushCare
View full PlushCare review →Rating
8.5/10
Monthly Price
$20Cheaper
Medications
semaglutidetirzepatideliraglutide
Pros
- ✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
- ✓Membership is $19.99/month with the first month free, and there is no minimum commitment
- ✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
- ✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
- ✓A full refund is offered if the doctor is unable to treat you
- ✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
- ✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
- ✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure
Cons
- ✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
- ✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
- ✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
- ✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
- ✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
- ✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
- ✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
- ✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site
LifeMD
View full LifeMD review →Rating
8.5/10
Monthly Price
$199
Medications
semaglutidetirzepatide
Pros
- ✓Prescribes FDA-approved branded GLP-1s - Zepbound and Wegovy - rather than compounded preparations, so you get the exact product the trials studied
- ✓Accepts insurance including Medicare, and advertises as low as $0 copay for branded GLP-1s where coverage applies
- ✓Publishes cash prices too: Wegovy Pen from $199/month and Zepbound Vial from $349/month (checked July 28, 2026)
- ✓Offers an outcome-based guarantee: 'lose 10% of your weight or your money back', which ties the promise to a result rather than a satisfaction survey
- ✓HSA and FSA eligible
- ✓Weight care sits inside a full telehealth service, so urgent care, labs and other specialties are available under the same account
Cons
- ✗The rotating banner on the weight-management page shows the Wegovy Pen at both '$199' and '$499' in the same carousel, which makes the real starting price unclear before you sign up
- ✗The money-back guarantee carries a footnote marker on site, so read the qualifying conditions before relying on it
- ✗Insurance coverage for obesity medication is patchy, so the '$0 copay' outcome will not apply to many people and the cash prices are what you should plan around
- ✗A 4.0 Trustpilot average is mid-range for this category
- ✗Branded GLP-1s at $199-$349/month are more expensive than compounded alternatives, which is the trade-off for using an FDA-approved product
- ✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy
Feature-by-feature comparison
| Feature | PlushCare | LifeMD |
|---|---|---|
| Monthly Price | $20 | $199 |
| Rating | 8.5/10 | 8.5/10 |
| Medications | semaglutide, tirzepatide, liraglutide | semaglutide, tirzepatide |
| Insurance Accepted | Yes | Yes |
| Support Hours | Video visits available 24/7 | Mon-Fri 8AM-8PM ET |
| Live Chat | No | Available |
| Free Shipping | No | Yes |
| Shipping Speed | Filled at your pharmacy; not shipped by PlushCare | 3-5 days |
| Mobile App | Available | Available |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Ongoing management with a board-certified primary care physician | Quarterly |
| Money-back Guarantee | Full refund if the doctor is unable to treat you; medication and lab costs are never included | Lose 10% of your weight or your money back (conditions apply) |
| Cancellation Policy | Cancel anytime, no minimum commitment; first month of membership is free | Cancel anytime |
Which should you choose?
Choose PlushCare if you:
- →Want to save $179/month with a more affordable option
- →Want more medication options to choose from
- →Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit
Choose LifeMD if you:
- →Value: prescribes fda-approved branded glp-1s - zepbound and wegovy - rather than compounded preparations, so you get the exact product the trials studied
Website previews
PlushCare
LifeMD
Our recommendation
PlushCare offers better value at $20/month while maintaining strong ratings. It also provides multiple medication options including both semaglutide and tirzepatide.
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