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PlushCare vs Live Vital

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

PlushCare vs Live Vital: Overview

Choosing between PlushCare and Live Vital for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. Live Vital also provides both semaglutide and tirzepatide at $149/month with a 6.4/10 rating.

The price difference of $129/month is significant - PlushCare is the more budget-friendly option, while Live Vital positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$129/mo

Rating Difference

2.1

Winner

PlushCare

Best For

Budget

PlushCare

View full PlushCare review →

Rating

8.5/10Better

Monthly Price

$20Cheaper

Medications

semaglutidetirzepatideliraglutide

Pros

✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
✓Membership is $19.99/month with the first month free, and there is no minimum commitment
✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
✓A full refund is offered if the doctor is unable to treat you
✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site

Choose PlushCare

Live Vital

View full Live Vital review →

Rating

6.4/10

Monthly Price

$149

Medications

tesamorelinMOTS-cBPC-157TB-500CJC-1295/IpamorelinNAD+GHK-Cuglutathione

Pros

✓Every protocol is priced openly on one page: glutathione $66/mo, NAD+ $83/mo, GHK-Cu $99/mo, Wolverine and CJC-1295/Ipamorelin $116/mo, Glow, Klow and MOTS-c $149/mo, tesamorelin $166/mo (checked July 28, 2026)
✓A named, identifiable physician stands behind the service, and a free 15-minute phone consult with him is offered before you buy
✓It publishes a dedicated peptide therapy informed consent document covering risks, benefits and alternatives - genuinely rare in this corner of the market
✓Telehealth consent and a HIPAA notice are published alongside the usual terms and privacy policy
✓Products are prescribed after a medical intake and prepared by a licensed US pharmacy, with unlimited messaging included
✓Available in all 50 states, per the company

Cons

✗This is not a GLP-1 weight loss service. Live Vital sells no semaglutide and no tirzepatide - its 'Weight & metabolism' line is tesamorelin and MOTS-c, which work through entirely different mechanisms
✗Two of its headline ingredients, BPC-157 and TB-500, were placed by the FDA on its 503A Category 2 list - bulk substances identified as raising significant safety risks in compounding. They appear here both standalone and inside the Glow, Klow and Wolverine blends
✗MOTS-c and KPV have essentially no published human trial evidence for the benefits described, yet MOTS-c is sold as a weight and metabolism protocol at $149/mo
✗Tesamorelin is described as 'An FDA-studied analog that targets stubborn abdominal fat'. Its actual FDA approval is for HIV-associated lipodystrophy specifically, not general abdominal fat, and the compounded version sold here is not the approved product
✗We could not find any statement that these compounded peptides are not FDA-approved
✗No refund or cancellation policy appears among the published legal documents
✗No independent review record exists - no Trustpilot profile, no BBB file, no displayed rating
✗No published phone number or support hours beyond the booked consult

Choose Live Vital

Feature-by-feature comparison

Feature	PlushCare	Live Vital
Monthly Price	$20	$149
Rating	8.5/10	6.4/10
Medications	semaglutide, tirzepatide, liraglutide	tesamorelin, MOTS-c, BPC-157, TB-500, CJC-1295/Ipamorelin, NAD+, GHK-Cu, glutathione
Insurance Accepted	Yes	No
Support Hours	Video visits available 24/7	Not published
Live Chat	No	No
Free Shipping	No	Yes
Shipping Speed	Filled at your pharmacy; not shipped by PlushCare	Not published
Mobile App	Available	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing management with a board-certified primary care physician	Unlimited messaging with the care team
Money-back Guarantee	Full refund if the doctor is unable to treat you; medication and lab costs are never included	None published
Cancellation Policy	Cancel anytime, no minimum commitment; first month of membership is free	Not published among the legal documents

Which should you choose?

Choose PlushCare if you:

→Want to save $129/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 6.4/10)
→Need insurance coverage for your treatment
→Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Get started with PlushCare

Choose Live Vital if you:

→Want more medication options to choose from
→Value: every protocol is priced openly on one page: glutathione $66/mo, nad+ $83/mo, ghk-cu $99/mo, wolverine and cjc-1295/ipamorelin $116/mo, glow, klow and mots-c $149/mo, tesamorelin $166/mo (checked july 28, 2026)

Get started with Live Vital

Website previews

PlushCare

PlushCare website

Live Vital

Live Vital website

Our recommendation

PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with PlushCare

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