PlushCare vs MangoRx
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
PlushCare vs MangoRx: Overview
Choosing between PlushCare and MangoRx for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. MangoRx also provides both semaglutide and tirzepatide at $299/month with a 7.4/10 rating.
The price difference of $279/month is significant - PlushCare is the more budget-friendly option, while MangoRx positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$279/mo
Rating Difference
1.1
Winner
PlushCare
Best For
Budget
PlushCare
View full PlushCare review →Rating
8.5/10Better
Monthly Price
$20Cheaper
Medications
semaglutidetirzepatideliraglutide
Pros
- ✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
- ✓Membership is $19.99/month with the first month free, and there is no minimum commitment
- ✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
- ✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
- ✓A full refund is offered if the doctor is unable to treat you
- ✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
- ✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
- ✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure
Cons
- ✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
- ✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
- ✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
- ✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
- ✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
- ✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
- ✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
- ✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site
MangoRx
View full MangoRx review →Rating
7.4/10
Monthly Price
$299
Medications
oral semaglutidetestosteronesildenafiltadalafil
Pros
- ✓Pricing is published without an intake and stated as locked in with no hidden fees: Slim oral semaglutide at $299/month and TRT starting at $99/month (checked July 28, 2026)
- ✓Provider visits and shipping are free on all orders, so there is no separate consultation fee stacked on top
- ✓The TRT program includes a comprehensive lab test and a personalized plan, with a full refund if you do not qualify - so the assessment carries no financial risk
- ✓The compounded-medication disclosure is thorough and correctly worded, including the point that clinical data from FDA-approved drugs may not transfer to compounded versions
- ✓It explicitly disclaims any relationship with Novo Nordisk or Eli Lilly rather than trading on their brand names
- ✓An orally dissolving tablet is a genuine convenience for people who will not inject, and the formulation adds vitamin B6, which the site says is intended to reduce nausea
- ✓Replied to 100% of negative Trustpilot reviews
- ✓A dedicated safety page, pharmacy disclaimer and telehealth consent are all published and dated
Cons
- ✗At $299/month, Slim is one of the more expensive semaglutide options we cover - and it is compounded. For comparison, the FDA-approved oral semaglutide listed elsewhere on this site sits at $149/month, so you would be paying roughly double for a preparation the FDA has not reviewed
- ✗There is no published bioavailability data for this tablet. Approved oral semaglutide relies on an absorption enhancer (SNAC) plus a strict fasting-and-water protocol precisely because semaglutide is a peptide that is poorly absorbed by mouth. Without that data, there is no way to know how much drug a compounded orally dissolving tablet actually delivers
- ✗The weight-loss figures associated with semaglutide - roughly 14.9% of body weight over 68 weeks in the STEP-1 trial - come from weekly subcutaneous injections of the branded drug, not from a compounded oral tablet. Do not assume the results transfer
- ✗The FDA declared the semaglutide shortage resolved in early 2025, after which compounders were required to stop producing what amounts to a copy of an approved drug. Providers still selling compounded semaglutide generally argue their formulation is materially different. It is a fair question to put to the provider before paying
- ✗The refund policy covers dispensing errors, cancellation before filling, and shipping damage reported within 7 days. It does not cover simply not getting on with the treatment
- ✗Only 15 Trustpilot reviews, and no BBB profile, so there is very little independent evidence either way
- ✗No corporate entity, address or phone number appears anywhere on the site - support is a single email address
- ✗This offer is not available in Alabama, Alaska, Arkansas, California, Kentucky, Louisiana, Michigan, Mississippi, North Dakota, South Carolina, South Dakota or Wyoming
- ✗The brand voice leans heavily on bravado - 'MAN. GO.', 'You badass' - which sits oddly against prescribing a GLP-1 and testosterone, where the tone you want is clinical caution
- ✗Semaglutide is not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, and is not for use in pregnancy. Pancreatitis and gallbladder disease are recognised risks
Feature-by-feature comparison
| Feature | PlushCare | MangoRx |
|---|---|---|
| Monthly Price | $20 | $299 |
| Rating | 8.5/10 | 7.4/10 |
| Medications | semaglutide, tirzepatide, liraglutide | oral semaglutide, testosterone, sildenafil, tadalafil |
| Insurance Accepted | Yes | No |
| Support Hours | Video visits available 24/7 | Not published |
| Live Chat | No | No |
| Free Shipping | No | Yes |
| Shipping Speed | Filled at your pharmacy; not shipped by PlushCare | Free discreet shipping on all orders; Slim ships monthly as a 30-day supply |
| Mobile App | Available | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Ongoing management with a board-certified primary care physician | Doctor-managed plans with lab-based adjustment on TRT; cadence not published |
| Money-back Guarantee | Full refund if the doctor is unable to treat you; medication and lab costs are never included | Full refund on TRT if you do not qualify. Otherwise refunds are limited to dispensing errors, pre-fill cancellation, or shipping damage reported within 7 days |
| Cancellation Policy | Cancel anytime, no minimum commitment; first month of membership is free | Monthly supply; cancellation before a prescription is filled is refundable, subject to the cancellation policy |
Which should you choose?
Choose PlushCare if you:
- →Want to save $279/month with a more affordable option
- →Prefer a higher-rated service (8.5/10 vs 7.4/10)
- →Need insurance coverage for your treatment
- →Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit
Choose MangoRx if you:
- →Want more medication options to choose from
- →Value: pricing is published without an intake and stated as locked in with no hidden fees: slim oral semaglutide at $299/month and trt starting at $99/month (checked july 28, 2026)
Website previews
PlushCare
MangoRx
Our recommendation
PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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