← All providers

PlushCare vs TMates

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

PlushCare vs TMates: Overview

Choosing between PlushCare and TMates for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. TMates also provides both semaglutide and tirzepatide at $249/month with a 7.8/10 rating.

The price difference of $229/month is significant - PlushCare is the more budget-friendly option, while TMates positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$229/mo

Rating Difference

0.7

Winner

PlushCare

Best For

Budget

PlushCare

View full PlushCare review →

Rating

8.5/10Better

Monthly Price

$20Cheaper

Medications

semaglutidetirzepatideliraglutide

Pros

✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
✓Membership is $19.99/month with the first month free, and there is no minimum commitment
✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
✓A full refund is offered if the doctor is unable to treat you
✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site

Choose PlushCare

TMates

View full TMates review →

Rating

7.8/10

Monthly Price

$249

Medications

semaglutidetirzepatide

Pros

✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
✓Both injectable and oral formats are offered at the same published prices
✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms

Cons

✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
✗No published customer phone number, support email or support hours
✗No BBB profile or complaint record to check

Feature-by-feature comparison

Feature	PlushCare	TMates
Monthly Price	$20	$249
Rating	8.5/10	7.8/10
Medications	semaglutide, tirzepatide, liraglutide	semaglutide, tirzepatide
Insurance Accepted	Yes	No
Support Hours	Video visits available 24/7	Not published
Live Chat	No	No
Free Shipping	No	Yes
Shipping Speed	Filled at your pharmacy; not shipped by PlushCare	Free shipping; timeframe not published
Mobile App	Available	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing management with a board-certified primary care physician	Ongoing provider support included
Money-back Guarantee	Full refund if the doctor is unable to treat you; medication and lab costs are never included	None published
Cancellation Policy	Cancel anytime, no minimum commitment; first month of membership is free	Cancel anytime, but multi-month plans are paid upfront

Which should you choose?

Choose PlushCare if you:

→Want to save $229/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 7.8/10)
→Want more medication options to choose from
→Need insurance coverage for your treatment
→Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Get started with PlushCare

Choose TMates if you:

→Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026

Get started with TMates

Website previews

PlushCare

PlushCare website

TMates

TMates website

Our recommendation

PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with PlushCare

Related comparisons

PlushCare vs CoreAge Rx

PlushCare vs Zepbound

PlushCare vs Mounjaro

PlushCare vs Wegovy Pill

PlushCare vs Foundayo

PlushCare vs Wegovy

PlushCare vs NovoCare Pharmacy

PlushCare vs Ozempic

PlushCare vs Form Health

PlushCare vs Henry Meds

PlushCare vs Sesame Care

PlushCare vs FuturHealth

PlushCare vs Circle Medical

PlushCare vs Ro

PlushCare vs Midi Health

PlushCare vs Noom Med

PlushCare vs Precision Telemed

PlushCare vs Hims

PlushCare vs Calibrate

PlushCare vs LifeMD

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand