PlushCare vs Winona
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
PlushCare vs Winona: Overview
Choosing between PlushCare and Winona for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
PlushCare offers both semaglutide and tirzepatide at $20/month with a rating of 8.5/10. Winona also provides both semaglutide and tirzepatide at $89/month with a 8.4/10 rating.
The price difference of $69/month is significant - PlushCare is the more budget-friendly option, while Winona positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$69/mo
Rating Difference
0.1
Winner
PlushCare
Best For
Budget
PlushCare
View full PlushCare review →Rating
8.5/10Better
Monthly Price
$20Cheaper
Medications
semaglutidetirzepatideliraglutide
Pros
- ✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
- ✓Membership is $19.99/month with the first month free, and there is no minimum commitment
- ✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
- ✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
- ✓A full refund is offered if the doctor is unable to treat you
- ✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
- ✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
- ✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure
Cons
- ✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
- ✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
- ✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
- ✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
- ✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
- ✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
- ✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
- ✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site
Winona
View full Winona review →Rating
8.4/10
Monthly Price
$89
Medications
bioidentical estradiolprogesteroneestriolDHEAsildenafilminoxidil
Pros
- ✓The full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked July 28, 2026)
- ✓Multiple delivery routes are offered - patch, body cream, vaginal cream, tablet and capsule - so treatment can be matched to preference rather than to whatever the company happens to stock
- ✓Winona owns its own 503A compounding pharmacies rather than outsourcing to a partner, which gives it direct control over formulation and consistency
- ✓Its pharmacy page explains the 503A/503B distinction correctly and states that 503A pharmacies are regulated by State Boards of Pharmacy, not the FDA - an accurate description that competitors routinely overstate
- ✓Roughly 8,000 Trustpilot reviews at 4.6, with 99% of negative reviews answered and a typical reply time under 24 hours
- ✓The rating advertised on site matches the rating on the public Trustpilot profile
- ✓The initial visit is free, so you can be assessed before paying for treatment
- ✓Editorial content carries numbered citations rather than unsourced assertions, and the site runs a public subreddit alongside a help centre and published phone number
- ✓HSA/FSA eligible, with a dedicated page explaining eligibility
- ✓Adjacent products are priced transparently too - DHEA from $27 per 3-month supply, sildenafil arousal cream at $79 per order, minoxidil hair serum at $150 per 3-month supply
Cons
- ✗Everything Winona dispenses is compounded in its own 503A pharmacies, which means it is not FDA-approved and has not been evaluated by the FDA for safety, efficacy or quality. The site explains 503A status clearly but does not foreground the 'not FDA-approved' consequence as plainly
- ✗Pharmaceutical products cannot be returned, per the terms - so once a prescription ships, you own it
- ✗The terms carry a mandatory arbitration clause on an individual basis with a class-action waiver, set out in capitals at the top of the document
- ✗Every headline price is a 'from' figure, so the actual monthly cost depends on the dose your clinician prescribes and is not knowable before the consultation
- ✗The hormone therapy explainer describes HRT as 'scientifically proven to be the safest, most effective treatment' for menopause symptoms. It is cited, but that is a strong framing for a therapy whose risk profile still depends heavily on age, time since menopause and personal history
- ✗Trustpilot notes Winona invites customers to review, which tends to lift scores relative to organic-only profiles, and that it may use AI-assisted replies
- ✗Systemic estrogen is not appropriate for everyone - women with a history of breast or endometrial cancer, unexplained vaginal bleeding, blood clots, stroke or liver disease should not start it without specialist input
- ✗Compounded hormone therapy in general lacks the long-term outcome data that exists for FDA-approved products, so the evidence cited for HRT as a class does not transfer automatically to these specific preparations
Feature-by-feature comparison
| Feature | PlushCare | Winona |
|---|---|---|
| Monthly Price | $20 | $89 |
| Rating | 8.5/10 | 8.4/10 |
| Medications | semaglutide, tirzepatide, liraglutide | bioidentical estradiol, progesterone, estriol, DHEA, sildenafil, minoxidil |
| Insurance Accepted | Yes | No |
| Support Hours | Video visits available 24/7 | Help centre and chat available; hours not published |
| Live Chat | No | Available |
| Free Shipping | No | Yes |
| Shipping Speed | Filled at your pharmacy; not shipped by PlushCare | Shipped to your door after clinician review; free shipping included |
| Mobile App | Available | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Ongoing management with a board-certified primary care physician | Ongoing clinician access through the patient portal; cadence not published |
| Money-back Guarantee | Full refund if the doctor is unable to treat you; medication and lab costs are never included | None published; pharmaceutical products cannot be returned. A separate cancellation and refund policy governs subscriptions |
| Cancellation Policy | Cancel anytime, no minimum commitment; first month of membership is free | Subscriptions can be cancelled from your account; a separate cancellation policy governs when it takes effect |
Which should you choose?
Choose PlushCare if you:
- →Want to save $69/month with a more affordable option
- →Prefer a higher-rated service (8.5/10 vs 8.4/10)
- →Need insurance coverage for your treatment
- →Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit
Choose Winona if you:
- →Want more medication options to choose from
- →Value: the full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked july 28, 2026)
Website previews
PlushCare
Winona
Our recommendation
PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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