RxSpan MD vs MEDVi Quad

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

RxSpan MD vs MEDVi Quad: Overview

Choosing between RxSpan MD and MEDVi Quad for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

RxSpan MD offers both semaglutide and tirzepatide at $249/month with a rating of 7.6/10. MEDVi Quad also provides both semaglutide and tirzepatide at $114/month with a 6.5/10 rating.

The price difference of $135/month is significant - MEDVi Quad is the more budget-friendly option, while RxSpan MD positions itself as a premium service.

VERIFIED

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$135/mo
Rating Difference
1.1
Winner
RxSpan MD
Best For
Quality

RxSpan MD

View full RxSpan MD review →
Rating
7.6/10Better
Monthly Price
$249
Medications
semaglutidetirzepatide

Pros

  • A full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked July 27, 2026)
  • Brand-name options are offered and priced openly too - Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069
  • The plan ladder is shown with each rate: $249/mo monthly, $219/mo on 3 months, $199/mo on 6 months and $194/mo on 12 months
  • The price is stated to include the consult, medication, supplies, shipping and support, with no separate membership fee
  • Oral capsule versions of both semaglutide and tirzepatide are available for people who do not want injections
  • Plans can be cancelled or changed at any time
  • The site states plainly that 'Prescription is not guaranteed' rather than implying approval is automatic
  • A named, credentialled physician is associated with the service rather than an anonymous 'medical team'

Cons

  • Every headline price is labelled 'For the first month'. What you pay from month two is not shown anywhere on the product screen, so the ongoing cost is unknown until you are further into the funnel
  • You pay at checkout before a provider reviews your case - the site confirms 'After checkout, a provider will review your information to determine if treatment is right for you' - so your money goes first and eligibility is decided afterwards
  • There is no independent review signal at all: no Trustpilot profile, no BBB file, and no rating displayed on site
  • Brand-name pricing is far above the manufacturers' own direct-pay programmes - $1,349 for Wegovy and $1,069 for Zepbound against considerably cheaper NovoCare and LillyDirect routes
  • No customer phone number is published; the only contact is an email address
  • The supervising physician's board certification is in plastic surgery, not obesity medicine, endocrinology or internal medicine
  • The banner copy - 'No Hidden Fees', 'Free, Expedited Delivery', 'Doctor-led Plans & Coaching' - is word-for-word identical to TrimRx's, indicating a shared white-label funnel rather than an independently built service
  • Product prices only render once JavaScript loads; with scripts blocked the weight-loss category reads 'No products found for Weight Loss'
Choose RxSpan MD

MEDVi Quad

View full MEDVi Quad review →
Rating
6.5/10
Monthly Price
$114Cheaper
Medications
sildenafiltadalafilbremelanotide (PT-141)L-citrulline

Pros

  • $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked July 28, 2026)
  • Cancel anytime, and the page states you are not charged if you do not qualify
  • All four active ingredients are named openly - PT-141 (bremelanotide), L-citrulline, sildenafil and tadalafil - rather than hidden behind a proprietary blend name
  • Sublingual delivery is a real advantage over tablets: it bypasses first-pass metabolism, so onset is faster and a heavy meal does not blunt absorption the way it can with oral sildenafil
  • Backed by a substantial independent review record - roughly 14,000 Trustpilot reviews at 4.4, with 99% of negative reviews answered
  • A published phone number, email address and physical address, which many competitors in this category omit entirely

Cons

  • 'Peak rigidity guaranteed' appears directly in the product copy. No prescription medication can guarantee an outcome, and this is the most explicit outcome promise we have seen across every provider reviewed on this site
  • The formula stacks two PDE5 inhibitors - sildenafil and tadalafil - and then adds L-citrulline, a nitric oxide precursor. All three act on the same nitric oxide and cGMP pathway, so the blood-pressure-lowering effect compounds three ways rather than one
  • PT-141 adds a fourth agent that independently causes low blood pressure, nausea and flushing. Four actives, four routes to hypotension, and no discussion anywhere on the page of the combined risk
  • Bremelanotide's only FDA approval is as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Prescribing it to men in a compounded sublingual liquid is off-label and a different route of administration
  • The word FDA does not appear on the page at all. The product is compounded, and the page never states the consequence - that compounded preparations are not reviewed or approved by the FDA for safety, efficacy or quality
  • 'The world's first 4-in-1 formula' and 'hospital-grade power' are unverifiable marketing superlatives attached to a prescription product
  • The advertised Trustpilot score covers MEDVi's business as a whole rather than this specific product
  • The published address is a suite at a Delaware registered-agent building, not a clinical facility
  • Anyone taking nitrates or riociguat must not use this product. The PT-141 component also interacts with 5-HT3 anti-emetics such as ondansetron, and stacking two PDE5 inhibitors makes the nitrate contraindication more dangerous, not less
Choose MEDVi Quad

Feature-by-feature comparison

FeatureRxSpan MDMEDVi Quad
Monthly Price$249$114
Rating7.6/106.5/10
Medicationssemaglutide, tirzepatidesildenafil, tadalafil, bremelanotide (PT-141), L-citrulline
Insurance AcceptedNoNo
Support HoursNot published24/7 medical support advertised
Live ChatNoNo
Free ShippingYesYes
Shipping SpeedFree expedited delivery claimed; timeframe not publishedFree rush shipping included in the monthly price
Mobile AppNoNo
Dedicated CoachIncludedNot included
Follow-up FrequencyDoctor-led plans and coaching advertised; frequency not published24/7 medical support advertised; follow-up cadence not published
Money-back GuaranteeNone published; you are charged at checkout before a provider decides whether to prescribeNo charge if you do not qualify; no refund policy published for dispensed medication
Cancellation PolicyCancel or change plans at any timeCancel anytime

Which should you choose?

Choose RxSpan MD if you:

  • Prefer a higher-rated service (7.6/10 vs 6.5/10)
  • Want personalized coaching support included
  • Value: a full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked july 27, 2026)

Choose MEDVi Quad if you:

  • Want to save $135/month with a more affordable option
  • Want more medication options to choose from
  • Value: $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked july 28, 2026)

Website previews

RxSpan MD

RxSpan MD website

MEDVi Quad

MEDVi Quad website

Our recommendation

RxSpan MD comes out ahead with a higher rating of 7.6/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with RxSpan MD

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