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RxSpan MD vs Willow

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

RxSpan MD vs Willow: Overview

Choosing between RxSpan MD and Willow for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

RxSpan MD offers both semaglutide and tirzepatide at $249/month with a rating of 7.6/10. Willow also provides both semaglutide and tirzepatide at $299/month with a 7.4/10 rating.

With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$50/mo

Rating Difference

0.2

Winner

RxSpan MD

Best For

Budget

RxSpan MD

View full RxSpan MD review →

Rating

7.6/10Better

Monthly Price

$249Cheaper

Medications

semaglutidetirzepatide

Pros

✓A full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked July 27, 2026)
✓Brand-name options are offered and priced openly too - Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069
✓The plan ladder is shown with each rate: $249/mo monthly, $219/mo on 3 months, $199/mo on 6 months and $194/mo on 12 months
✓The price is stated to include the consult, medication, supplies, shipping and support, with no separate membership fee
✓Oral capsule versions of both semaglutide and tirzepatide are available for people who do not want injections
✓Plans can be cancelled or changed at any time
✓The site states plainly that 'Prescription is not guaranteed' rather than implying approval is automatic
✓A named, credentialled physician is associated with the service rather than an anonymous 'medical team'

Cons

✗Every headline price is labelled 'For the first month'. What you pay from month two is not shown anywhere on the product screen, so the ongoing cost is unknown until you are further into the funnel
✗You pay at checkout before a provider reviews your case - the site confirms 'After checkout, a provider will review your information to determine if treatment is right for you' - so your money goes first and eligibility is decided afterwards
✗There is no independent review signal at all: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Brand-name pricing is far above the manufacturers' own direct-pay programmes - $1,349 for Wegovy and $1,069 for Zepbound against considerably cheaper NovoCare and LillyDirect routes
✗No customer phone number is published; the only contact is an email address
✗The supervising physician's board certification is in plastic surgery, not obesity medicine, endocrinology or internal medicine
✗The banner copy - 'No Hidden Fees', 'Free, Expedited Delivery', 'Doctor-led Plans & Coaching' - is word-for-word identical to TrimRx's, indicating a shared white-label funnel rather than an independently built service
✗Product prices only render once JavaScript loads; with scripts blocked the weight-loss category reads 'No products found for Weight Loss'

Choose RxSpan MD

Willow

View full Willow review →

Rating

7.4/10

Monthly Price

$299

Medications

semaglutidetirzepatide

Pros

✓Flat published pricing: $299/mo for compounded semaglutide as a weekly injection or a daily tablet, and $399/mo for compounded tirzepatide (checked July 26, 2026)
✓One fee covers the medical evaluation, the medication, unlimited doctor messaging and free discreet shipping, with no separate consultation charge
✓Names its partner pharmacies in its terms - Red Rock Home Pharmacy (Springville, UT), Epiq Pharmacy / Epiq Scripts (Richardson, TX) and The Pharmacy Hub (Miami, FL) - which most compounded GLP-1 sellers do not do
✓Publishes a Florida telehealth provider registration number (TPME1718) and names the exact states it is licensed to serve
✓The 'compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA' disclaimer sits on the homepage itself, not buried in a footer
✓Full refund if you cancel before the prescription is submitted to the pharmacy, processed within 5-10 business days
✓Needle-free daily tablets available for both semaglutide and tirzepatide, and the program is HSA/FSA eligible
✓Same-day prescription review claimed, with support from a named care team

Cons

✗In December 2025 the National Advertising Division found Willow had not substantiated its weight-loss and efficacy claims for compounded semaglutide, Willow declined to comply, and NAD referred it to state attorneys general and ad platforms. That is the most serious independent mark against any provider on this site
✗At $299-$399 a month this is one of the more expensive compounded GLP-1 programs; several competitors advertise $149-$199
✗The flat rate is not locked. The terms state your subscription fee 'may be increased or decreased if your prescription changes, such as by a dosage increase or frequency of refills', so titrating up can raise your bill
✗The site advertises '4.9/5 (2200 + 5 star reviews)' with no source named. Trustpilot, the one public platform we could find, showed 3.8 from 351 reviews on July 26, 2026
✗Cancellation must be received two full calendar days before your next shipping date, or the next order ships and bills
✗The terms tell you to cancel at startwillow.com/contact/ - that URL returned a 404 when we checked, as did the site's /contact and /help-center pages
✗No customer phone number or support email is published anywhere on the public site
✗The published terms are dated November 24, 2021, well before the current product line and pricing
✗Not available nationwide: Willow's terms limit service to 36 states, and this offer in particular is not available in Alabama, Alaska, Arkansas, Delaware, Kansas, Louisiana, Maine, Massachusetts, Mississippi, New Mexico, North Dakota, Rhode Island, South Dakota, Tennessee, Utah, Vermont, West Virginia or Wyoming
✗No insurance billing, and the terms confirm Medicare and Medicaid do not cover the service

Feature-by-feature comparison

Feature	RxSpan MD	Willow
Monthly Price	$249	$299
Rating	7.6/10	7.4/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	24/7 online support claimed
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free expedited delivery claimed; timeframe not published	Not published; same-day prescription review claimed
Mobile App	No	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Doctor-led plans and coaching advertised; frequency not published	Unlimited doctor messaging and free follow-ups claimed
Money-back Guarantee	None published; you are charged at checkout before a provider decides whether to prescribe	Full refund only if you cancel before the prescription reaches the pharmacy; no returns on medication once dispensed
Cancellation Policy	Cancel or change plans at any time	Cancel anytime, but the request must arrive two full calendar days before your next shipping date

Which should you choose?

Choose RxSpan MD if you:

→Want to save $50/month with a more affordable option
→Prefer a higher-rated service (7.6/10 vs 7.4/10)
→Want personalized coaching support included
→Value: a full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked july 27, 2026)

Get started with RxSpan MD

Choose Willow if you:

→Value: flat published pricing: $299/mo for compounded semaglutide as a weekly injection or a daily tablet, and $399/mo for compounded tirzepatide (checked july 26, 2026)

Get started with Willow

Website previews

RxSpan MD

RxSpan MD website

Willow

Willow website

Our recommendation

RxSpan MD comes out ahead with a higher rating of 7.6/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with RxSpan MD

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