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Shameless Care vs Harper Meds

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Shameless Care vs Harper Meds: Overview

Choosing between Shameless Care and Harper Meds for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Shameless Care offers both semaglutide and tirzepatide at $109/month with a rating of 8/10. Harper Meds also provides both semaglutide and tirzepatide at $149/month with a 6.5/10 rating.

With only a $40/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$40/mo

Rating Difference

1.5

Winner

Shameless Care

Best For

Budget

Shameless Care

View full Shameless Care review →

Rating

8/10Better

Monthly Price

$109Cheaper

Medications

sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline

Pros

✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost

Cons

✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
✗Not available in all 50 states - the site states 49
✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron

Choose Shameless Care

Harper Meds

View full Harper Meds review →

Rating

6.5/10

Monthly Price

$149

Medications

semaglutidetirzepatide

Pros

✓Published pricing from $149/month, with a second tier from $196/month
✓No insurance needed and no hidden fees, stated on the site
✓The site carries a results-may-vary disclaimer on its compounded medications

Cons

✗The FDA has formally told Harper Meds that its labelling and its "same active ingredient as Ozempic" claim misrepresented its compounded products - see the warning letter above
✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
✗The "less than $5/day" framing converts to roughly $150 a month and is designed to sound smaller
✗No phone number, refund policy or pharmacy named

Choose Harper Meds

Feature-by-feature comparison

Feature	Shameless Care	Harper Meds
Monthly Price	$109	$149
Rating	8/10	6.5/10
Medications	sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost	Not published
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Board-certified physician assigned from start to finish; ongoing cadence not published	Not published
Money-back Guarantee	Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published	None published
Cancellation Policy	No subscriptions - every purchase is one-off, so there is nothing to cancel	Not published

Which should you choose?

Choose Shameless Care if you:

→Want to save $40/month with a more affordable option
→Prefer a higher-rated service (8/10 vs 6.5/10)
→Want more medication options to choose from
→Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)

Get started with Shameless Care

Choose Harper Meds if you:

→Value: published pricing from $149/month, with a second tier from $196/month

Get started with Harper Meds

Website previews

Shameless Care

Shameless Care website

Harper Meds

Harper Meds website

Our recommendation

Shameless Care comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Shameless Care

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