Shameless Care vs IVY RX
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Shameless Care vs IVY RX: Overview
Choosing between Shameless Care and IVY RX for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Shameless Care offers both semaglutide and tirzepatide at $109/month with a rating of 8/10. IVY RX also provides both semaglutide and tirzepatide at $97/month with a 8/10 rating.
With only a $12/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$12/mo
Rating Difference
0.0
Winner
IVY RX
Best For
Budget
Shameless Care
View full Shameless Care review →Rating
8/10
Monthly Price
$109
Medications
sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline
Pros
- ✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
- ✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
- ✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
- ✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
- ✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
- ✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
- ✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
- ✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
- ✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
- ✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost
Cons
- ✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
- ✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
- ✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
- ✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
- ✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
- ✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
- ✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
- ✗Not available in all 50 states - the site states 49
- ✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron
IVY RX
View full IVY RX review →Rating
8/10
Monthly Price
$97Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓The lowest advertised GLP-1 pricing we have found: $97 for the standard GLP-1 injection and $77 for the microdose plan (checked July 27, 2026)
- ✓The on-site rating is real and verifiable - 4.7 from 6,549 Trustpilot reviews, matching what the site claims
- ✓Publishes a phone line, a support email and a physical address, with support advertised seven days a week
- ✓Every product carries its own 'Important safety information' section rather than one generic sitewide disclaimer
- ✓Brand-name Ozempic and Mounjaro are offered alongside compounded options
- ✓Needle-free GLP-1 oral melts and a microdose plan give lower-intensity entry points
- ✓Anti-nausea tablets are sold alongside the GLP-1s, which is a practical acknowledgement of the most common side effect
- ✓The compounded disclosure sits next to the products themselves, not buried in a policy page
Cons
- ✗The refund policy gives you no defined entitlement. It states IVY RX is 'unable to accept returns' and then invites you to 'contact us so we can work together to find a solution' - there is no stated circumstance in which you are owed money back
- ✗The storefront labels its weight-loss products generically as 'GLP-1' and 'GLP-1 Microdose' rather than naming semaglutide or tirzepatide, so you cannot tell which molecule you are buying until later in the flow
- ✗No plan terms are published for the $97 rate - there is nothing on the page saying whether it requires a multi-month commitment
- ✗The catalogue includes BPC 157 and methylene blue under a 'Supplements' menu. BPC-157 is a peptide the FDA has flagged over compounding safety, and neither is an approved dietary ingredient, so their presence is a reason for caution about the wider range
- ✗Two different support addresses appear across the site - hello@ivyrx.com in the header and support@ivyrx.com in the refund policy
- ✗Ozempic and Mounjaro are FDA-approved for type 2 diabetes, so prescribing them for weight loss is off-label
- ✗No BBB profile or complaint record to set against the Trustpilot score
- ✗As with all compounded GLP-1s, the products are not FDA-approved and no efficacy data specific to IVY RX's patients is published
Feature-by-feature comparison
| Feature | Shameless Care | IVY RX |
|---|---|---|
| Monthly Price | $109 | $97 |
| Rating | 8/10 | 8/10 |
| Medications | sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Not published | Seven days a week (hours not published) |
| Live Chat | No | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost | Fast and free delivery claimed; timeframe not published |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Board-certified physician assigned from start to finish; ongoing cadence not published | Not published |
| Money-back Guarantee | Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published | None - the policy states returns cannot be accepted and offers no defined refund entitlement |
| Cancellation Policy | No subscriptions - every purchase is one-off, so there is nothing to cancel | Not published as a standalone policy; contact support to resolve issues |
Which should you choose?
Choose Shameless Care if you:
- →Want more medication options to choose from
- →Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)
Choose IVY RX if you:
- →Want to save $12/month with a more affordable option
- →Value: the lowest advertised glp-1 pricing we have found: $97 for the standard glp-1 injection and $77 for the microdose plan (checked july 27, 2026)
Website previews
Shameless Care
IVY RX
Our recommendation
IVY RX offers better value at $97/month while maintaining strong ratings. It also provides multiple medication options including both semaglutide and tirzepatide.
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