Shameless Care vs US Scripts MD
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Shameless Care vs US Scripts MD: Overview
Choosing between Shameless Care and US Scripts MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Shameless Care offers both semaglutide and tirzepatide at $109/month with a rating of 8/10. US Scripts MD also provides both semaglutide and tirzepatide at $299/month with a 7/10 rating.
The price difference of $190/month is significant - Shameless Care is the more budget-friendly option, while US Scripts MD positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$190/mo
Rating Difference
1.0
Winner
Shameless Care
Best For
Budget
Shameless Care
View full Shameless Care review →Rating
8/10Better
Monthly Price
$109Cheaper
Medications
sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline
Pros
- ✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
- ✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
- ✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
- ✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
- ✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
- ✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
- ✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
- ✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
- ✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
- ✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost
Cons
- ✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
- ✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
- ✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
- ✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
- ✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
- ✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
- ✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
- ✗Not available in all 50 states - the site states 49
- ✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron
US Scripts MD
View full US Scripts MD review →Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide
Pros
- ✓One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
- ✓No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
- ✓Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
- ✓Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
- ✓An injection kit with spare syringes is included in every shipment
- ✓Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
- ✓24/7 access to board-certified doctor support is advertised
- ✓You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
- ✓A $100 discount on the first month of weight-loss treatment
Cons
- ✗Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
- ✗The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
- ✗Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
- ✗The medication is compounded and not FDA-approved
- ✗The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
- ✗The dispensing pharmacy is not named
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗No published phone number
Feature-by-feature comparison
| Feature | Shameless Care | US Scripts MD |
|---|---|---|
| Monthly Price | $109 | $299 |
| Rating | 8/10 | 7/10 |
| Medications | sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline | liraglutide, semaglutide |
| Insurance Accepted | No | No |
| Support Hours | Not published | Company advertises 24/7 access to partnering board-certified doctors |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost | Free overnight shipping in temperature-controlled packaging |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Board-certified physician assigned from start to finish; ongoing cadence not published | 24/7 access to partnering board-certified doctors for questions and support |
| Money-back Guarantee | Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published | Full refund if the medical providers determine you are not a fit for the programme |
| Cancellation Policy | No subscriptions - every purchase is one-off, so there is nothing to cancel | Cancel any time before your order ships; no contracts |
Which should you choose?
Choose Shameless Care if you:
- →Want to save $190/month with a more affordable option
- →Prefer a higher-rated service (8/10 vs 7/10)
- →Want more medication options to choose from
- →Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)
Choose US Scripts MD if you:
- →Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1
Website previews
Shameless Care
US Scripts MD
Our recommendation
Shameless Care comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with Shameless CareRelated comparisons
Shameless Care vs CoreAge Rx
$109
★ 8
vs
$99
★ 9.6
Shameless Care vs Zepbound
$109
★ 8
vs
$450
★ 9.3
Shameless Care vs Mounjaro
$109
★ 8
vs
$1080
★ 9.2
Shameless Care vs Wegovy Pill
$109
★ 8
vs
$149
★ 9.2
Shameless Care vs Foundayo
$109
★ 8
vs
$149
★ 9.2
Shameless Care vs Wegovy
$109
★ 8
vs
$349
★ 9.1
Shameless Care vs NovoCare Pharmacy
$109
★ 8
vs
$149
★ 9
Shameless Care vs Ozempic
$109
★ 8
vs
$349
★ 8.9
Shameless Care vs Form Health
$109
★ 8
vs
$299
★ 8.8
Shameless Care vs Henry Meds
$109
★ 8
vs
$179
★ 8.7
Shameless Care vs Sesame Care
$109
★ 8
vs
$59
★ 8.7
Shameless Care vs FuturHealth
$109
★ 8
vs
$225
★ 8.7
Shameless Care vs Circle Medical
$109
★ 8
vs
$35
★ 8.7
Shameless Care vs Ro
$109
★ 8
vs
$149
★ 8.6
Shameless Care vs Midi Health
$109
★ 8
vs
$164
★ 8.6
Shameless Care vs Noom Med
$109
★ 8
vs
$149
★ 8.6
Shameless Care vs Precision Telemed
$109
★ 8
vs
$150
★ 8.6
Shameless Care vs Hims
$109
★ 8
vs
$298
★ 8.5
Shameless Care vs Calibrate
$109
★ 8
vs
$199
★ 8.5
Shameless Care vs PlushCare
$109
★ 8
vs
$20
★ 8.5
Compare other providers
Compare GLP-1 Brands
vs