Shameless Care vs Willow
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Shameless Care vs Willow: Overview
Choosing between Shameless Care and Willow for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Shameless Care offers both semaglutide and tirzepatide at $109/month with a rating of 8/10. Willow also provides both semaglutide and tirzepatide at $299/month with a 7.4/10 rating.
The price difference of $190/month is significant - Shameless Care is the more budget-friendly option, while Willow positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$190/mo
Rating Difference
0.6
Winner
Shameless Care
Best For
Budget
Shameless Care
View full Shameless Care review →Rating
8/10Better
Monthly Price
$109Cheaper
Medications
sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline
Pros
- ✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
- ✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
- ✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
- ✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
- ✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
- ✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
- ✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
- ✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
- ✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
- ✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost
Cons
- ✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
- ✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
- ✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
- ✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
- ✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
- ✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
- ✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
- ✗Not available in all 50 states - the site states 49
- ✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron
Willow
View full Willow review →Rating
7.4/10
Monthly Price
$299
Medications
semaglutidetirzepatide
Pros
- ✓Flat published pricing: $299/mo for compounded semaglutide as a weekly injection or a daily tablet, and $399/mo for compounded tirzepatide (checked July 26, 2026)
- ✓One fee covers the medical evaluation, the medication, unlimited doctor messaging and free discreet shipping, with no separate consultation charge
- ✓Names its partner pharmacies in its terms - Red Rock Home Pharmacy (Springville, UT), Epiq Pharmacy / Epiq Scripts (Richardson, TX) and The Pharmacy Hub (Miami, FL) - which most compounded GLP-1 sellers do not do
- ✓Publishes a Florida telehealth provider registration number (TPME1718) and names the exact states it is licensed to serve
- ✓The 'compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA' disclaimer sits on the homepage itself, not buried in a footer
- ✓Full refund if you cancel before the prescription is submitted to the pharmacy, processed within 5-10 business days
- ✓Needle-free daily tablets available for both semaglutide and tirzepatide, and the program is HSA/FSA eligible
- ✓Same-day prescription review claimed, with support from a named care team
Cons
- ✗In December 2025 the National Advertising Division found Willow had not substantiated its weight-loss and efficacy claims for compounded semaglutide, Willow declined to comply, and NAD referred it to state attorneys general and ad platforms. That is the most serious independent mark against any provider on this site
- ✗At $299-$399 a month this is one of the more expensive compounded GLP-1 programs; several competitors advertise $149-$199
- ✗The flat rate is not locked. The terms state your subscription fee 'may be increased or decreased if your prescription changes, such as by a dosage increase or frequency of refills', so titrating up can raise your bill
- ✗The site advertises '4.9/5 (2200 + 5 star reviews)' with no source named. Trustpilot, the one public platform we could find, showed 3.8 from 351 reviews on July 26, 2026
- ✗Cancellation must be received two full calendar days before your next shipping date, or the next order ships and bills
- ✗The terms tell you to cancel at startwillow.com/contact/ - that URL returned a 404 when we checked, as did the site's /contact and /help-center pages
- ✗No customer phone number or support email is published anywhere on the public site
- ✗The published terms are dated November 24, 2021, well before the current product line and pricing
- ✗Not available nationwide: Willow's terms limit service to 36 states, and this offer in particular is not available in Alabama, Alaska, Arkansas, Delaware, Kansas, Louisiana, Maine, Massachusetts, Mississippi, New Mexico, North Dakota, Rhode Island, South Dakota, Tennessee, Utah, Vermont, West Virginia or Wyoming
- ✗No insurance billing, and the terms confirm Medicare and Medicaid do not cover the service
Feature-by-feature comparison
| Feature | Shameless Care | Willow |
|---|---|---|
| Monthly Price | $109 | $299 |
| Rating | 8/10 | 7.4/10 |
| Medications | sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Not published | 24/7 online support claimed |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost | Not published; same-day prescription review claimed |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Board-certified physician assigned from start to finish; ongoing cadence not published | Unlimited doctor messaging and free follow-ups claimed |
| Money-back Guarantee | Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published | Full refund only if you cancel before the prescription reaches the pharmacy; no returns on medication once dispensed |
| Cancellation Policy | No subscriptions - every purchase is one-off, so there is nothing to cancel | Cancel anytime, but the request must arrive two full calendar days before your next shipping date |
Which should you choose?
Choose Shameless Care if you:
- →Want to save $190/month with a more affordable option
- →Prefer a higher-rated service (8/10 vs 7.4/10)
- →Want more medication options to choose from
- →Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)
Choose Willow if you:
- →Value: flat published pricing: $299/mo for compounded semaglutide as a weekly injection or a daily tablet, and $399/mo for compounded tirzepatide (checked july 26, 2026)
Website previews
Shameless Care
Willow
Our recommendation
Shameless Care comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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