Trimi Health vs Shameless Care
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Trimi Health vs Shameless Care: Overview
Choosing between Trimi Health and Shameless Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Trimi Health offers both semaglutide and tirzepatide at $175/month with a rating of 8.2/10. Shameless Care also provides both semaglutide and tirzepatide at $109/month with a 8/10 rating.
The price difference of $66/month is significant - Shameless Care is the more budget-friendly option, while Trimi Health positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$66/mo
Rating Difference
0.2
Winner
Trimi Health
Best For
Quality
Trimi Health
View full Trimi Health review →Rating
8.2/10Better
Monthly Price
$175
Medications
semaglutidetirzepatide
Pros
- ✓Publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked July 26, 2026
- ✓Compounded tirzepatide advertised from $125/mo on annual billing, flat across every dose so titrating up does not raise your bill
- ✓The refund policy is the clearest we have read in this category: cancel any time before a clinician issues your prescription for a full refund with no fees, and a full refund including the consultation fee if a clinician decides you are not a fit
- ✓It also explains why the cutoff exists, citing USP <795> and <797> rules on patient-specific compounded sterile preparations rather than just asserting that sales are final
- ✓A 6-month money-back promise: follow the plan and your provider's guidance for six months and, if you have not lost weight, you can request a refund of the plan fees (terms apply)
- ✓Clinical care is provided by a named network, Arora Health, and the compounded status is disclosed repeatedly - the medications are 'not FDA-approved as drugs'
- ✓Free overnight shipping, FSA/HSA eligibility, and Affirm, Klarna and Afterpay financing at checkout
- ✓Damaged or missing deliveries are handled within 24 hours by replacement, refund or carrier claim
Cons
- ✗The headline $99/mo requires paying $1,188 up front for a year. Billed monthly the same treatment is $175 - a 77% difference the landing page does not put next to the $99
- ✗The site markets compounded semaglutide as the 'Same active ingredient as Wegovy' and tirzepatide as 'Same as Mounjaro'. That is the exact claim type the FDA cited in its February 2026 warning letter to another telehealth firm, on the basis that it implies the compounded product has been FDA-approved when it has not
- ✗Efficacy figures are borrowed from trials of the branded drugs and then applied to compounded copies and to individual readers - 'You could lose 44 lbs per the 22% clinical average'. No compounded product has been through those trials
- ✗The '22% clinical average' overstates the source: tirzepatide's SURMOUNT-1 trial reported about 20.9% mean weight loss at the top 15 mg dose over 72 weeks
- ✗The '4.5' rating and '50,233+ patients' shown on the site carry no source, and we could not find a Trustpilot profile for the domain to check either figure
- ✗Once a clinician issues your prescription the order is final and non-refundable, even if the medication has not shipped
- ✗Trimi publishes provider ranking articles that place Trimi first - 'Cheapest Tirzepatide Providers 2026: Trimi $125/mo of 10 Ranked' - and a guide titled 'How to Cancel TrimRx & Switch to Trimi'. Treat that content as marketing, not independent research
- ✗No BBB profile and no public complaint history means there is little independent record to check before you commit to an annual plan
Shameless Care
View full Shameless Care review →Rating
8/10
Monthly Price
$109Cheaper
Medications
sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline
Pros
- ✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
- ✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
- ✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
- ✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
- ✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
- ✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
- ✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
- ✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
- ✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
- ✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost
Cons
- ✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
- ✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
- ✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
- ✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
- ✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
- ✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
- ✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
- ✗Not available in all 50 states - the site states 49
- ✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron
Feature-by-feature comparison
| Feature | Trimi Health | Shameless Care |
|---|---|---|
| Monthly Price | $175 | $109 |
| Rating | 8.2/10 | 8/10 |
| Medications | semaglutide, tirzepatide | sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline |
| Insurance Accepted | No | No |
| Support Hours | Support advertised 24/7 via the patient portal | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free overnight shipping claimed | Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | 24/7 provider messaging and ongoing check-ins included | Board-certified physician assigned from start to finish; ongoing cadence not published |
| Money-back Guarantee | Full refund before a prescription is issued, plus a 6-month money-back promise if you follow the plan and do not lose weight (terms apply) | Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published |
| Cancellation Policy | Cancel any time before your prescription is issued for a full refund; once issued, the order is final | No subscriptions - every purchase is one-off, so there is nothing to cancel |
Which should you choose?
Choose Trimi Health if you:
- →Prefer a higher-rated service (8.2/10 vs 8/10)
- →Value: publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked july 26, 2026
Choose Shameless Care if you:
- →Want to save $66/month with a more affordable option
- →Want more medication options to choose from
- →Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)
Website previews
Trimi Health
Shameless Care
Our recommendation
Trimi Health comes out ahead with a higher rating of 8.2/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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