US Scripts MD vs Amie
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
US Scripts MD vs Amie: Overview
Choosing between US Scripts MD and Amie for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
US Scripts MD offers both semaglutide and tirzepatide at $299/month with a rating of 7/10. Amie also provides both semaglutide and tirzepatide at $99/month with a 6.5/10 rating.
The price difference of $200/month is significant - Amie is the more budget-friendly option, while US Scripts MD positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$200/mo
Rating Difference
0.5
Winner
US Scripts MD
Best For
Quality
US Scripts MD
View full US Scripts MD review →Rating
7/10Better
Monthly Price
$299
Medications
liraglutidesemaglutide
Pros
- ✓One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
- ✓No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
- ✓Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
- ✓Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
- ✓An injection kit with spare syringes is included in every shipment
- ✓Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
- ✓24/7 access to board-certified doctor support is advertised
- ✓You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
- ✓A $100 discount on the first month of weight-loss treatment
Cons
- ✗Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
- ✗The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
- ✗Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
- ✗The medication is compounded and not FDA-approved
- ✗The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
- ✗The dispensing pharmacy is not named
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗No published phone number
Amie
View full Amie review →Rating
6.5/10
Monthly Price
$99Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓Pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
- ✓No shipment unless a provider approves you, stated on the pricing panel
- ✓Optional add-ons are priced separately and openly rather than bundled in silently
Cons
- ✗The FDA has formally told Amie that its website misrepresented its compounded products - see the warning letter above
- ✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
- ✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
- ✗The three-month rate requires paying $249 up front
- ✗No phone number or support hours published
Feature-by-feature comparison
| Feature | US Scripts MD | Amie |
|---|---|---|
| Monthly Price | $299 | $99 |
| Rating | 7/10 | 6.5/10 |
| Medications | liraglutide, semaglutide | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Company advertises 24/7 access to partnering board-certified doctors | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free overnight shipping in temperature-controlled packaging | Not published; no shipment unless approved |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | 24/7 access to partnering board-certified doctors for questions and support | Not published |
| Money-back Guarantee | Full refund if the medical providers determine you are not a fit for the programme | None published |
| Cancellation Policy | Cancel any time before your order ships; no contracts | Monthly or 3-month plans; terms not summarised on the pricing panel |
Which should you choose?
Choose US Scripts MD if you:
- →Prefer a higher-rated service (7/10 vs 6.5/10)
- →Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1
Choose Amie if you:
- →Want to save $200/month with a more affordable option
- →Value: pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
Website previews
US Scripts MD
Amie
Our recommendation
US Scripts MD comes out ahead with a higher rating of 7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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