US Scripts MD vs LifeMD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

US Scripts MD vs LifeMD: Overview

Choosing between US Scripts MD and LifeMD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

US Scripts MD offers both semaglutide and tirzepatide at $299/month with a rating of 7/10. LifeMD also provides both semaglutide and tirzepatide at $199/month with a 8.5/10 rating.

The price difference of $100/month is significant - LifeMD is the more budget-friendly option, while US Scripts MD positions itself as a premium service.

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Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$100/mo
Rating Difference
1.5
Winner
LifeMD
Best For
Budget

US Scripts MD

View full US Scripts MD review →
Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide

Pros

  • One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
  • No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
  • Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
  • Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
  • An injection kit with spare syringes is included in every shipment
  • Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
  • 24/7 access to board-certified doctor support is advertised
  • You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
  • A $100 discount on the first month of weight-loss treatment

Cons

  • Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
  • The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
  • Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
  • The medication is compounded and not FDA-approved
  • The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
  • The dispensing pharmacy is not named
  • No insurance billing, and HSA/FSA acceptance is not stated
  • No published phone number
Choose US Scripts MD

LifeMD

View full LifeMD review →
Rating
8.5/10Better
Monthly Price
$199Cheaper
Medications
semaglutidetirzepatide

Pros

  • Prescribes FDA-approved branded GLP-1s - Zepbound and Wegovy - rather than compounded preparations, so you get the exact product the trials studied
  • Accepts insurance including Medicare, and advertises as low as $0 copay for branded GLP-1s where coverage applies
  • Publishes cash prices too: Wegovy Pen from $199/month and Zepbound Vial from $349/month (checked July 28, 2026)
  • Offers an outcome-based guarantee: 'lose 10% of your weight or your money back', which ties the promise to a result rather than a satisfaction survey
  • HSA and FSA eligible
  • Weight care sits inside a full telehealth service, so urgent care, labs and other specialties are available under the same account

Cons

  • The rotating banner on the weight-management page shows the Wegovy Pen at both '$199' and '$499' in the same carousel, which makes the real starting price unclear before you sign up
  • The money-back guarantee carries a footnote marker on site, so read the qualifying conditions before relying on it
  • Insurance coverage for obesity medication is patchy, so the '$0 copay' outcome will not apply to many people and the cash prices are what you should plan around
  • A 4.0 Trustpilot average is mid-range for this category
  • Branded GLP-1s at $199-$349/month are more expensive than compounded alternatives, which is the trade-off for using an FDA-approved product
  • GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy
Choose LifeMD

Feature-by-feature comparison

FeatureUS Scripts MDLifeMD
Monthly Price$299$199
Rating7/108.5/10
Medicationsliraglutide, semaglutidesemaglutide, tirzepatide
Insurance AcceptedNoYes
Support HoursCompany advertises 24/7 access to partnering board-certified doctorsMon-Fri 8AM-8PM ET
Live ChatNoAvailable
Free ShippingYesYes
Shipping SpeedFree overnight shipping in temperature-controlled packaging3-5 days
Mobile AppNoAvailable
Dedicated CoachNot includedNot included
Follow-up Frequency24/7 access to partnering board-certified doctors for questions and supportQuarterly
Money-back GuaranteeFull refund if the medical providers determine you are not a fit for the programmeLose 10% of your weight or your money back (conditions apply)
Cancellation PolicyCancel any time before your order ships; no contractsCancel anytime

Which should you choose?

Choose US Scripts MD if you:

  • Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1

Choose LifeMD if you:

  • Want to save $100/month with a more affordable option
  • Prefer a higher-rated service (8.5/10 vs 7/10)
  • Need insurance coverage for your treatment
  • Value: prescribes fda-approved branded glp-1s - zepbound and wegovy - rather than compounded preparations, so you get the exact product the trials studied

Website previews

US Scripts MD

US Scripts MD website

LifeMD

LifeMD website

Our recommendation

LifeMD comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with LifeMD

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