US Scripts MD vs MangoRx
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
US Scripts MD vs MangoRx: Overview
Choosing between US Scripts MD and MangoRx for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
US Scripts MD offers both semaglutide and tirzepatide at $299/month with a rating of 7/10. MangoRx also provides both semaglutide and tirzepatide at $299/month with a 7.4/10 rating.
With only a $0/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$0/mo
Rating Difference
0.4
Winner
MangoRx
Best For
Quality
US Scripts MD
View full US Scripts MD review →Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide
Pros
- ✓One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
- ✓No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
- ✓Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
- ✓Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
- ✓An injection kit with spare syringes is included in every shipment
- ✓Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
- ✓24/7 access to board-certified doctor support is advertised
- ✓You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
- ✓A $100 discount on the first month of weight-loss treatment
Cons
- ✗Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
- ✗The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
- ✗Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
- ✗The medication is compounded and not FDA-approved
- ✗The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
- ✗The dispensing pharmacy is not named
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗No published phone number
MangoRx
View full MangoRx review →Rating
7.4/10Better
Monthly Price
$299
Medications
oral semaglutidetestosteronesildenafiltadalafil
Pros
- ✓Pricing is published without an intake and stated as locked in with no hidden fees: Slim oral semaglutide at $299/month and TRT starting at $99/month (checked July 28, 2026)
- ✓Provider visits and shipping are free on all orders, so there is no separate consultation fee stacked on top
- ✓The TRT program includes a comprehensive lab test and a personalized plan, with a full refund if you do not qualify - so the assessment carries no financial risk
- ✓The compounded-medication disclosure is thorough and correctly worded, including the point that clinical data from FDA-approved drugs may not transfer to compounded versions
- ✓It explicitly disclaims any relationship with Novo Nordisk or Eli Lilly rather than trading on their brand names
- ✓An orally dissolving tablet is a genuine convenience for people who will not inject, and the formulation adds vitamin B6, which the site says is intended to reduce nausea
- ✓Replied to 100% of negative Trustpilot reviews
- ✓A dedicated safety page, pharmacy disclaimer and telehealth consent are all published and dated
Cons
- ✗At $299/month, Slim is one of the more expensive semaglutide options we cover - and it is compounded. For comparison, the FDA-approved oral semaglutide listed elsewhere on this site sits at $149/month, so you would be paying roughly double for a preparation the FDA has not reviewed
- ✗There is no published bioavailability data for this tablet. Approved oral semaglutide relies on an absorption enhancer (SNAC) plus a strict fasting-and-water protocol precisely because semaglutide is a peptide that is poorly absorbed by mouth. Without that data, there is no way to know how much drug a compounded orally dissolving tablet actually delivers
- ✗The weight-loss figures associated with semaglutide - roughly 14.9% of body weight over 68 weeks in the STEP-1 trial - come from weekly subcutaneous injections of the branded drug, not from a compounded oral tablet. Do not assume the results transfer
- ✗The FDA declared the semaglutide shortage resolved in early 2025, after which compounders were required to stop producing what amounts to a copy of an approved drug. Providers still selling compounded semaglutide generally argue their formulation is materially different. It is a fair question to put to the provider before paying
- ✗The refund policy covers dispensing errors, cancellation before filling, and shipping damage reported within 7 days. It does not cover simply not getting on with the treatment
- ✗Only 15 Trustpilot reviews, and no BBB profile, so there is very little independent evidence either way
- ✗No corporate entity, address or phone number appears anywhere on the site - support is a single email address
- ✗This offer is not available in Alabama, Alaska, Arkansas, California, Kentucky, Louisiana, Michigan, Mississippi, North Dakota, South Carolina, South Dakota or Wyoming
- ✗The brand voice leans heavily on bravado - 'MAN. GO.', 'You badass' - which sits oddly against prescribing a GLP-1 and testosterone, where the tone you want is clinical caution
- ✗Semaglutide is not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, and is not for use in pregnancy. Pancreatitis and gallbladder disease are recognised risks
Feature-by-feature comparison
| Feature | US Scripts MD | MangoRx |
|---|---|---|
| Monthly Price | $299 | $299 |
| Rating | 7/10 | 7.4/10 |
| Medications | liraglutide, semaglutide | oral semaglutide, testosterone, sildenafil, tadalafil |
| Insurance Accepted | No | No |
| Support Hours | Company advertises 24/7 access to partnering board-certified doctors | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free overnight shipping in temperature-controlled packaging | Free discreet shipping on all orders; Slim ships monthly as a 30-day supply |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | 24/7 access to partnering board-certified doctors for questions and support | Doctor-managed plans with lab-based adjustment on TRT; cadence not published |
| Money-back Guarantee | Full refund if the medical providers determine you are not a fit for the programme | Full refund on TRT if you do not qualify. Otherwise refunds are limited to dispensing errors, pre-fill cancellation, or shipping damage reported within 7 days |
| Cancellation Policy | Cancel any time before your order ships; no contracts | Monthly supply; cancellation before a prescription is filled is refundable, subject to the cancellation policy |
Which should you choose?
Choose US Scripts MD if you:
- →Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1
Choose MangoRx if you:
- →Prefer a higher-rated service (7.4/10 vs 7/10)
- →Want more medication options to choose from
- →Value: pricing is published without an intake and stated as locked in with no hidden fees: slim oral semaglutide at $299/month and trt starting at $99/month (checked july 28, 2026)
Website previews
US Scripts MD
MangoRx
Our recommendation
MangoRx comes out ahead with a higher rating of 7.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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