US Scripts MD vs MEDVi Quad

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

US Scripts MD vs MEDVi Quad: Overview

Choosing between US Scripts MD and MEDVi Quad for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

US Scripts MD offers both semaglutide and tirzepatide at $299/month with a rating of 7/10. MEDVi Quad also provides both semaglutide and tirzepatide at $114/month with a 6.5/10 rating.

The price difference of $185/month is significant - MEDVi Quad is the more budget-friendly option, while US Scripts MD positions itself as a premium service.

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Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$185/mo
Rating Difference
0.5
Winner
US Scripts MD
Best For
Quality

US Scripts MD

View full US Scripts MD review →
Rating
7/10Better
Monthly Price
$299
Medications
liraglutidesemaglutide

Pros

  • One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
  • No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
  • Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
  • Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
  • An injection kit with spare syringes is included in every shipment
  • Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
  • 24/7 access to board-certified doctor support is advertised
  • You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
  • A $100 discount on the first month of weight-loss treatment

Cons

  • Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
  • The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
  • Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
  • The medication is compounded and not FDA-approved
  • The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
  • The dispensing pharmacy is not named
  • No insurance billing, and HSA/FSA acceptance is not stated
  • No published phone number
Choose US Scripts MD

MEDVi Quad

View full MEDVi Quad review →
Rating
6.5/10
Monthly Price
$114Cheaper
Medications
sildenafiltadalafilbremelanotide (PT-141)L-citrulline

Pros

  • $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked July 28, 2026)
  • Cancel anytime, and the page states you are not charged if you do not qualify
  • All four active ingredients are named openly - PT-141 (bremelanotide), L-citrulline, sildenafil and tadalafil - rather than hidden behind a proprietary blend name
  • Sublingual delivery is a real advantage over tablets: it bypasses first-pass metabolism, so onset is faster and a heavy meal does not blunt absorption the way it can with oral sildenafil
  • Backed by a substantial independent review record - roughly 14,000 Trustpilot reviews at 4.4, with 99% of negative reviews answered
  • A published phone number, email address and physical address, which many competitors in this category omit entirely

Cons

  • 'Peak rigidity guaranteed' appears directly in the product copy. No prescription medication can guarantee an outcome, and this is the most explicit outcome promise we have seen across every provider reviewed on this site
  • The formula stacks two PDE5 inhibitors - sildenafil and tadalafil - and then adds L-citrulline, a nitric oxide precursor. All three act on the same nitric oxide and cGMP pathway, so the blood-pressure-lowering effect compounds three ways rather than one
  • PT-141 adds a fourth agent that independently causes low blood pressure, nausea and flushing. Four actives, four routes to hypotension, and no discussion anywhere on the page of the combined risk
  • Bremelanotide's only FDA approval is as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Prescribing it to men in a compounded sublingual liquid is off-label and a different route of administration
  • The word FDA does not appear on the page at all. The product is compounded, and the page never states the consequence - that compounded preparations are not reviewed or approved by the FDA for safety, efficacy or quality
  • 'The world's first 4-in-1 formula' and 'hospital-grade power' are unverifiable marketing superlatives attached to a prescription product
  • The advertised Trustpilot score covers MEDVi's business as a whole rather than this specific product
  • The published address is a suite at a Delaware registered-agent building, not a clinical facility
  • Anyone taking nitrates or riociguat must not use this product. The PT-141 component also interacts with 5-HT3 anti-emetics such as ondansetron, and stacking two PDE5 inhibitors makes the nitrate contraindication more dangerous, not less
Choose MEDVi Quad

Feature-by-feature comparison

FeatureUS Scripts MDMEDVi Quad
Monthly Price$299$114
Rating7/106.5/10
Medicationsliraglutide, semaglutidesildenafil, tadalafil, bremelanotide (PT-141), L-citrulline
Insurance AcceptedNoNo
Support HoursCompany advertises 24/7 access to partnering board-certified doctors24/7 medical support advertised
Live ChatNoNo
Free ShippingYesYes
Shipping SpeedFree overnight shipping in temperature-controlled packagingFree rush shipping included in the monthly price
Mobile AppNoNo
Dedicated CoachNot includedNot included
Follow-up Frequency24/7 access to partnering board-certified doctors for questions and support24/7 medical support advertised; follow-up cadence not published
Money-back GuaranteeFull refund if the medical providers determine you are not a fit for the programmeNo charge if you do not qualify; no refund policy published for dispensed medication
Cancellation PolicyCancel any time before your order ships; no contractsCancel anytime

Which should you choose?

Choose US Scripts MD if you:

  • Prefer a higher-rated service (7/10 vs 6.5/10)
  • Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1

Choose MEDVi Quad if you:

  • Want to save $185/month with a more affordable option
  • Want more medication options to choose from
  • Value: $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked july 28, 2026)

Website previews

US Scripts MD

US Scripts MD website

MEDVi Quad

MEDVi Quad website

Our recommendation

US Scripts MD comes out ahead with a higher rating of 7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with US Scripts MD

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