US Scripts MD vs TrimRx
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
US Scripts MD vs TrimRx: Overview
Choosing between US Scripts MD and TrimRx for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
US Scripts MD offers both semaglutide and tirzepatide at $299/month with a rating of 7/10. TrimRx also provides both semaglutide and tirzepatide at $199/month with a 7.4/10 rating.
The price difference of $100/month is significant - TrimRx is the more budget-friendly option, while US Scripts MD positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$100/mo
Rating Difference
0.4
Winner
TrimRx
Best For
Budget
US Scripts MD
View full US Scripts MD review →Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide
Pros
- ✓One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
- ✓No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
- ✓Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
- ✓Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
- ✓An injection kit with spare syringes is included in every shipment
- ✓Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
- ✓24/7 access to board-certified doctor support is advertised
- ✓You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
- ✓A $100 discount on the first month of weight-loss treatment
Cons
- ✗Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
- ✗The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
- ✗Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
- ✗The medication is compounded and not FDA-approved
- ✗The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
- ✗The dispensing pharmacy is not named
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗No published phone number
TrimRx
View full TrimRx review →Rating
7.4/10Better
Monthly Price
$199Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓Published tier pricing you can read before you sign up: compounded GLP-1 at $174/mo month-to-month, $166 (3-month), $158 (6-month) or $149 (12-month); GLP-1 + GIP at $279, $266, $258 and $249 (checked July 26, 2026)
- ✓Same price at every dose, so your cost does not climb as you titrate up
- ✓The monthly fee bundles the telehealth visit, the medication, shipping and ongoing support - there is no separate consultation charge
- ✓Free 2-day shipping, and the terms commit to dispatch within 48 business hours of prescription approval
- ✓Unusually candid legal terms: TrimRx states in writing that compounded medications are not FDA-approved and makes no claim they are equivalent to the branded drugs
- ✓Providers will also write prescriptions for FDA-approved Ozempic ($1,299/mo) or Zepbound ($1,399/mo), fulfilled on a limited basis
- ✓BBB accredited since June 2025 and a LegitScript seal on site, with a real San Diego business address and published phone number
- ✓Available in all 50 states, with no insurance required
Cons
- ✗The advertised price is not the ongoing price. The terms list the GLP-1 follow-up month at $299 and GLP-1 + GIP at $399, while landing pages headline $149-$174. Those low rates require paying 3 to 12 months upfront
- ✗The 'lose weight or your money back' guarantee is contradicted twice over: the same landing page's disclaimer says weight loss is not guaranteed, and the refund policy allows refunds only for medical disqualification or a TrimRx billing error
- ✗Refund requests must be emailed within 28 days of payment; anything later, or sent through another channel, 'will not be honored'. Once your intake is submitted the order is non-refundable
- ✗The terms describe the opening offer as 'originally priced at $179, currently offered at $199' - the discounted price is higher than the original
- ✗Headline results (18% average weight loss, 93% 'kept the weight off for good', 6x more than diet and exercise) are footnoted as TrimRx's own patient data over six months, are not published anywhere, and cannot support a claim about keeping weight off permanently
- ✗Patient counts on a single page range from '10,000+' to 'over 100,000' to '350,000+'
- ✗The landing page shows a '4.9 Excellent Rating' in five gold stars with no source attached. The one public review platform we could find, Trustpilot, has TrimRx at 3.6 out of 5
- ✗Urgency devices throughout: a countdown timer, 'Only 9 Spots Left!', and a rotating stack of discounts ($120, $140, $200) that differs by landing page
- ✗One live funnel still carries a different brand's name ('THE TRINITYMEDS DIFFERENCE'), and the weight-loss calculator renders the placeholder text 'Missing variables: users'
- ✗No published clinician licence numbers, no live chat, and no insurance billing
Feature-by-feature comparison
| Feature | US Scripts MD | TrimRx |
|---|---|---|
| Monthly Price | $299 | $199 |
| Rating | 7/10 | 7.4/10 |
| Medications | liraglutide, semaglutide | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Company advertises 24/7 access to partnering board-certified doctors | 24/7 support claimed |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free overnight shipping in temperature-controlled packaging | Ships within 48 business hours, 1-2 day delivery claimed |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | 24/7 access to partnering board-certified doctors for questions and support | Unlimited messaging and appointments claimed |
| Money-back Guarantee | Full refund if the medical providers determine you are not a fit for the programme | Advertised as lose weight or your money back, but the terms allow refunds only for medical disqualification or a billing error, requested in writing within 28 days |
| Cancellation Policy | Cancel any time before your order ships; no contracts | Cancel anytime to stop future charges; processed charges are not refunded and orders are final once your intake is submitted |
Which should you choose?
Choose US Scripts MD if you:
- →Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1
Choose TrimRx if you:
- →Want to save $100/month with a more affordable option
- →Prefer a higher-rated service (7.4/10 vs 7/10)
- →Value: published tier pricing you can read before you sign up: compounded glp-1 at $174/mo month-to-month, $166 (3-month), $158 (6-month) or $149 (12-month); glp-1 + gip at $279, $266, $258 and $249 (checked july 26, 2026)
Website previews
US Scripts MD
TrimRx
Our recommendation
TrimRx comes out ahead with a higher rating of 7.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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