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Winona vs SkinnyRx

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Winona vs SkinnyRx: Overview

Choosing between Winona and SkinnyRx for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

Winona offers both semaglutide and tirzepatide at $89/month with a rating of 8.4/10. SkinnyRx also provides both semaglutide and tirzepatide at $199/month with a 8/10 rating.

The price difference of $110/month is significant - Winona is the more budget-friendly option, while SkinnyRx positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$110/mo

Rating Difference

0.4

Winner

Winona

Best For

Budget

Winona

View full Winona review →

Rating

8.4/10Better

Monthly Price

$89Cheaper

Medications

bioidentical estradiolprogesteroneestriolDHEAsildenafilminoxidil

Pros

✓The full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked July 28, 2026)
✓Multiple delivery routes are offered - patch, body cream, vaginal cream, tablet and capsule - so treatment can be matched to preference rather than to whatever the company happens to stock
✓Winona owns its own 503A compounding pharmacies rather than outsourcing to a partner, which gives it direct control over formulation and consistency
✓Its pharmacy page explains the 503A/503B distinction correctly and states that 503A pharmacies are regulated by State Boards of Pharmacy, not the FDA - an accurate description that competitors routinely overstate
✓Roughly 8,000 Trustpilot reviews at 4.6, with 99% of negative reviews answered and a typical reply time under 24 hours
✓The rating advertised on site matches the rating on the public Trustpilot profile
✓The initial visit is free, so you can be assessed before paying for treatment
✓Editorial content carries numbered citations rather than unsourced assertions, and the site runs a public subreddit alongside a help centre and published phone number
✓HSA/FSA eligible, with a dedicated page explaining eligibility
✓Adjacent products are priced transparently too - DHEA from $27 per 3-month supply, sildenafil arousal cream at $79 per order, minoxidil hair serum at $150 per 3-month supply

Cons

✗Everything Winona dispenses is compounded in its own 503A pharmacies, which means it is not FDA-approved and has not been evaluated by the FDA for safety, efficacy or quality. The site explains 503A status clearly but does not foreground the 'not FDA-approved' consequence as plainly
✗Pharmaceutical products cannot be returned, per the terms - so once a prescription ships, you own it
✗The terms carry a mandatory arbitration clause on an individual basis with a class-action waiver, set out in capitals at the top of the document
✗Every headline price is a 'from' figure, so the actual monthly cost depends on the dose your clinician prescribes and is not knowable before the consultation
✗The hormone therapy explainer describes HRT as 'scientifically proven to be the safest, most effective treatment' for menopause symptoms. It is cited, but that is a strong framing for a therapy whose risk profile still depends heavily on age, time since menopause and personal history
✗Trustpilot notes Winona invites customers to review, which tends to lift scores relative to organic-only profiles, and that it may use AI-assisted replies
✗Systemic estrogen is not appropriate for everyone - women with a history of breast or endometrial cancer, unexplained vaginal bleeding, blood clots, stroke or liver disease should not start it without specialist input
✗Compounded hormone therapy in general lacks the long-term outcome data that exists for FDA-approved products, so the evidence cited for HRT as a class does not transfer automatically to these specific preparations

SkinnyRx

View full SkinnyRx review →

Rating

8/10

Monthly Price

$199

Medications

semaglutidetirzepatide

Pros

✓Trustpilot rating of 4.8 across 5,272 reviews, an unusually strong independent signal for this category
✓Publishes a customer phone number, +1 (888) 979-9580, and a support email rather than hiding behind a portal
✓Full refund available any time before a licensed provider completes your prescription
✓Compounded injectable semaglutide from $199/month and tirzepatide, as tablets or injection, from $299/month, with microdose options (checked July 26, 2026)
✓Carefully separates compounded from brand-name in its own disclosures instead of implying the two are the same
✓Buy-now-pay-later through Affirm with the APR disclosed openly - the site gives a worked example of $800 split into 12 payments of $72.21 at 15% APR
✓A mobile app for meal plans, medication tracking and weight logging, plus unlimited provider messaging and free shipping
✓A substantial clinical content library covering practical issues like GLP-1s with levothyroxine, gallbladder pain and surgery timing

Cons

✗A '90-day money-back guarantee' is advertised in a banner on every page, but the site's own /money-back-guarantee link returns a 404 reading 'Page not found... Probably the link is broken'. We could not find the terms of that guarantee anywhere
✗The hero promises 'FDA-approved Wegovy, Foundayo and other GLP-1s', yet both the Wegovy Pill and Foundayo Pill are marked 'Unavailable' in the product list directly below
✗Pricing is at the higher end for compounded product: $199/month for semaglutide and $299/month for tirzepatide, where several rivals advertise under $150
✗'Lose up to 14.9% of your body weight' takes the figure from the STEP 1 trial of branded semaglutide and applies it to a compounded preparation that has not been trialled
✗The published refund window closes as soon as a provider completes your prescription, which can be the same day you sign up
✗A pop-up offers 'up to 43% off' without stating what plan or commitment unlocks that discount
✗No BBB profile or complaint history to cross-check the Trustpilot score against
✗No published support hours, so the phone line's availability is unknown

Choose SkinnyRx

Feature-by-feature comparison

Feature	Winona	SkinnyRx
Monthly Price	$89	$199
Rating	8.4/10	8/10
Medications	bioidentical estradiol, progesterone, estriol, DHEA, sildenafil, minoxidil	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Help centre and chat available; hours not published	Not published
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	Shipped to your door after clinician review; free shipping included	Not published
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing clinician access through the patient portal; cadence not published	Unlimited provider messaging plus app-based tracking
Money-back Guarantee	None published; pharmaceutical products cannot be returned. A separate cancellation and refund policy governs subscriptions	A 90-day money-back guarantee is advertised sitewide, but its terms page returns a 404; a full refund is available before a provider completes your prescription
Cancellation Policy	Subscriptions can be cancelled from your account; a separate cancellation policy governs when it takes effect	Cancel anytime; full refund only before the prescription is completed by a provider

Which should you choose?

Choose Winona if you:

→Want to save $110/month with a more affordable option
→Prefer a higher-rated service (8.4/10 vs 8/10)
→Want more medication options to choose from
→Value: the full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked july 28, 2026)

Get started with Winona

Choose SkinnyRx if you:

→Value: trustpilot rating of 4.8 across 5,272 reviews, an unusually strong independent signal for this category

Get started with SkinnyRx

Website previews

Winona

Winona website

SkinnyRx

SkinnyRx website

Our recommendation

Winona comes out ahead with a higher rating of 8.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Winona

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