Signos vs Ascend Medical
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Signos vs Ascend Medical: Overview
Choosing between Signos and Ascend Medical for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. Ascend Medical also provides both semaglutide and tirzepatide at $150/month with a 8.5/10 rating.
With only a $23/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$23/mo
Rating Difference
0.7
Winner
Ascend Medical
Best For
Quality
Signos
View full Signos review →Rating
7.8/10
Monthly Price
$127Cheaper
Medications
continuous glucose monitoring
Pros
- ✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
- ✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
- ✓Two CGM sensors per month are included in every plan
- ✓HSA/FSA eligible, which matters at these prices
- ✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
- ✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
- ✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
- ✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
- ✓Stress and sleep tracking are built in alongside glucose
Cons
- ✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
- ✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
- ✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
- ✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
- ✗The results guarantee pays out in a free data audit, not money back
- ✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
- ✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm
Ascend Medical
View full Ascend Medical review →Rating
8.5/10Better
Monthly Price
$150
Medications
semaglutidetirzepatide
Pros
- ✓Competitive pricing
- ✓Multiple medication options
- ✓Good support
- ✓Fast shipping
Cons
- ✗Newer company
- ✗Limited track record
- ✗Basic platform
Feature-by-feature comparison
| Feature | Signos | Ascend Medical |
|---|---|---|
| Monthly Price | $127 | $150 |
| Rating | 7.8/10 | 8.5/10 |
| Medications | continuous glucose monitoring | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | In-app dietitian chat; hours not published | Mon-Fri 9AM-7PM ET |
| Live Chat | Available | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free shipping; six-month plans ship in three-month bundles | 2-4 days |
| Mobile App | Available | Available |
| Dedicated Coach | Included | Not included |
| Follow-up Frequency | Continuous glucose data with in-app dietitian support | Monthly |
| Money-back Guarantee | 30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value) | 30-day refund |
| Cancellation Policy | Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused | Cancel anytime |
Which should you choose?
Choose Signos if you:
- →Want to save $23/month with a more affordable option
- →Want personalized coaching support included
- →Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
Choose Ascend Medical if you:
- →Prefer a higher-rated service (8.5/10 vs 7.8/10)
- →Want more medication options to choose from
- →Value: competitive pricing
Website previews
Signos
Ascend Medical
Our recommendation
Ascend Medical comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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