Signos vs Henry Meds
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Signos vs Henry Meds: Overview
Choosing between Signos and Henry Meds for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. Henry Meds also provides both semaglutide and tirzepatide at $179/month with a 8.7/10 rating.
The price difference of $52/month is significant - Signos is the more budget-friendly option, while Henry Meds positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$52/mo
Rating Difference
0.9
Winner
Henry Meds
Best For
Quality
Signos
View full Signos review →Rating
7.8/10
Monthly Price
$127Cheaper
Medications
continuous glucose monitoring
Pros
- ✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
- ✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
- ✓Two CGM sensors per month are included in every plan
- ✓HSA/FSA eligible, which matters at these prices
- ✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
- ✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
- ✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
- ✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
- ✓Stress and sleep tracking are built in alongside glucose
Cons
- ✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
- ✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
- ✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
- ✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
- ✗The results guarantee pays out in a free data audit, not money back
- ✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
- ✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm
Henry Meds
View full Henry Meds review →Rating
8.7/10Better
Monthly Price
$179
Medications
semaglutidetirzepatide
Pros
- ✓$179/month is genuinely all-in. Henry states the price 'includes the cost of your provider visits, medication, supplies, and ongoing support' - there is no separate membership fee stacked on top, which is the trap several competitors rely on
- ✓The compounding disclosure is the most complete and honest in this category, including the explicit warning that trial data for FDA-approved drugs should not be used to judge compounded versions
- ✓'Compounded Medications Prescribed Online' is the headline on the treatment page rather than fine print
- ✓Roughly 13,000 Trustpilot reviews at 4.4 - among the largest independent evidence bases of any brand on this site
- ✓Free evaluations are offered for many treatments, so you can be assessed before paying
- ✓Injection supplies are included with the medication rather than sold separately
- ✓No insurance required and no waiting rooms; the intake takes under five minutes
- ✓A published phone number and email address, which many competitors omit entirely
- ✓A broad service beyond weight care - women's HRT, testosterone therapy, erectile dysfunction and phentermine - so there is somewhere to go if a GLP-1 is not right for you
Cons
- ✗Cancelling early can cost you. The terms note you 'may be required to pay out the rest of your balance unless you're unable to continue for medical-related reasons as determined by a healthcare provider', so a plan is not simply walk-away
- ✗$179 is a 'starting at' figure that varies by treatment plan and dose, so your actual monthly cost is not knowable until after the medical assessment
- ✗Compounded semaglutide and tirzepatide are not FDA-approved. Henry says so clearly, but it remains the central limitation
- ✗No published states-served list, so eligibility is only confirmed during intake
- ✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy. Pancreatitis and gallbladder disease are recognised risks
Feature-by-feature comparison
| Feature | Signos | Henry Meds |
|---|---|---|
| Monthly Price | $127 | $179 |
| Rating | 7.8/10 | 8.7/10 |
| Medications | continuous glucose monitoring | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | In-app dietitian chat; hours not published | Mon-Sat 8AM-8PM ET |
| Live Chat | Available | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free shipping; six-month plans ship in three-month bundles | Medication and supplies mailed to your door if prescribed |
| Mobile App | Available | No |
| Dedicated Coach | Included | Included |
| Follow-up Frequency | Continuous glucose data with in-app dietitian support | Ongoing provider support included in the monthly price |
| Money-back Guarantee | 30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value) | Free evaluations offered; early cancellation may require paying out the remaining balance except for medical reasons |
| Cancellation Policy | Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused | No long-term contracts on monthly plans - cancel any time in the patient portal, by emailing ask@henrymeds.com or by calling 909-787-2342. On a multi-month plan you may be required to pay out the remaining balance unless a healthcare provider determines you cannot continue for medical reasons. |
Which should you choose?
Choose Signos if you:
- →Want to save $52/month with a more affordable option
- →Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
Choose Henry Meds if you:
- →Prefer a higher-rated service (8.7/10 vs 7.8/10)
- →Want more medication options to choose from
- →Value: $179/month is genuinely all-in. henry states the price 'includes the cost of your provider visits, medication, supplies, and ongoing support' - there is no separate membership fee stacked on top, which is the trap several competitors rely on
Website previews
Signos
Henry Meds
Our recommendation
Henry Meds comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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