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Signos vs IVY RX

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Signos vs IVY RX: Overview

Choosing between Signos and IVY RX for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. IVY RX also provides both semaglutide and tirzepatide at $97/month with a 8/10 rating.

With only a $30/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$30/mo

Rating Difference

0.2

Winner

IVY RX

Best For

Budget

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

IVY RX

View full IVY RX review →

Rating

8/10Better

Monthly Price

$97Cheaper

Medications

semaglutidetirzepatide

Pros

✓The lowest advertised GLP-1 pricing we have found: $97 for the standard GLP-1 injection and $77 for the microdose plan (checked July 27, 2026)
✓The on-site rating is real and verifiable - 4.7 from 6,549 Trustpilot reviews, matching what the site claims
✓Publishes a phone line, a support email and a physical address, with support advertised seven days a week
✓Every product carries its own 'Important safety information' section rather than one generic sitewide disclaimer
✓Brand-name Ozempic and Mounjaro are offered alongside compounded options
✓Needle-free GLP-1 oral melts and a microdose plan give lower-intensity entry points
✓Anti-nausea tablets are sold alongside the GLP-1s, which is a practical acknowledgement of the most common side effect
✓The compounded disclosure sits next to the products themselves, not buried in a policy page

Cons

✗The refund policy gives you no defined entitlement. It states IVY RX is 'unable to accept returns' and then invites you to 'contact us so we can work together to find a solution' - there is no stated circumstance in which you are owed money back
✗The storefront labels its weight-loss products generically as 'GLP-1' and 'GLP-1 Microdose' rather than naming semaglutide or tirzepatide, so you cannot tell which molecule you are buying until later in the flow
✗No plan terms are published for the $97 rate - there is nothing on the page saying whether it requires a multi-month commitment
✗The catalogue includes BPC 157 and methylene blue under a 'Supplements' menu. BPC-157 is a peptide the FDA has flagged over compounding safety, and neither is an approved dietary ingredient, so their presence is a reason for caution about the wider range
✗Two different support addresses appear across the site - hello@ivyrx.com in the header and support@ivyrx.com in the refund policy
✗Ozempic and Mounjaro are FDA-approved for type 2 diabetes, so prescribing them for weight loss is off-label
✗No BBB profile or complaint record to set against the Trustpilot score
✗As with all compounded GLP-1s, the products are not FDA-approved and no efficacy data specific to IVY RX's patients is published

Feature-by-feature comparison

Feature	Signos	IVY RX
Monthly Price	$127	$97
Rating	7.8/10	8/10
Medications	continuous glucose monitoring	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	In-app dietitian chat; hours not published	Seven days a week (hours not published)
Live Chat	Available	Available
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; six-month plans ship in three-month bundles	Fast and free delivery claimed; timeframe not published
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Continuous glucose data with in-app dietitian support	Not published
Money-back Guarantee	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)	None - the policy states returns cannot be accepted and offers no defined refund entitlement
Cancellation Policy	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused	Not published as a standalone policy; contact support to resolve issues

Which should you choose?

Choose Signos if you:

→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Choose IVY RX if you:

→Want to save $30/month with a more affordable option
→Prefer a higher-rated service (8/10 vs 7.8/10)
→Want more medication options to choose from
→Value: the lowest advertised glp-1 pricing we have found: $97 for the standard glp-1 injection and $77 for the microdose plan (checked july 27, 2026)

Get started with IVY RX

Website previews

Signos

Signos website

IVY RX

IVY RX website

Our recommendation

IVY RX comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with IVY RX

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