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Signos vs Live Vital

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Signos vs Live Vital: Overview

Choosing between Signos and Live Vital for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. Live Vital also provides both semaglutide and tirzepatide at $149/month with a 6.4/10 rating.

With only a $22/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$22/mo

Rating Difference

1.4

Winner

Signos

Best For

Budget

Signos

View full Signos review →

Rating

7.8/10Better

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Live Vital

View full Live Vital review →

Rating

6.4/10

Monthly Price

$149

Medications

tesamorelinMOTS-cBPC-157TB-500CJC-1295/IpamorelinNAD+GHK-Cuglutathione

Pros

✓Every protocol is priced openly on one page: glutathione $66/mo, NAD+ $83/mo, GHK-Cu $99/mo, Wolverine and CJC-1295/Ipamorelin $116/mo, Glow, Klow and MOTS-c $149/mo, tesamorelin $166/mo (checked July 28, 2026)
✓A named, identifiable physician stands behind the service, and a free 15-minute phone consult with him is offered before you buy
✓It publishes a dedicated peptide therapy informed consent document covering risks, benefits and alternatives - genuinely rare in this corner of the market
✓Telehealth consent and a HIPAA notice are published alongside the usual terms and privacy policy
✓Products are prescribed after a medical intake and prepared by a licensed US pharmacy, with unlimited messaging included
✓Available in all 50 states, per the company

Cons

✗This is not a GLP-1 weight loss service. Live Vital sells no semaglutide and no tirzepatide - its 'Weight & metabolism' line is tesamorelin and MOTS-c, which work through entirely different mechanisms
✗Two of its headline ingredients, BPC-157 and TB-500, were placed by the FDA on its 503A Category 2 list - bulk substances identified as raising significant safety risks in compounding. They appear here both standalone and inside the Glow, Klow and Wolverine blends
✗MOTS-c and KPV have essentially no published human trial evidence for the benefits described, yet MOTS-c is sold as a weight and metabolism protocol at $149/mo
✗Tesamorelin is described as 'An FDA-studied analog that targets stubborn abdominal fat'. Its actual FDA approval is for HIV-associated lipodystrophy specifically, not general abdominal fat, and the compounded version sold here is not the approved product
✗We could not find any statement that these compounded peptides are not FDA-approved
✗No refund or cancellation policy appears among the published legal documents
✗No independent review record exists - no Trustpilot profile, no BBB file, no displayed rating
✗No published phone number or support hours beyond the booked consult

Choose Live Vital

Feature-by-feature comparison

Feature	Signos	Live Vital
Monthly Price	$127	$149
Rating	7.8/10	6.4/10
Medications	continuous glucose monitoring	tesamorelin, MOTS-c, BPC-157, TB-500, CJC-1295/Ipamorelin, NAD+, GHK-Cu, glutathione
Insurance Accepted	No	No
Support Hours	In-app dietitian chat; hours not published	Not published
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; six-month plans ship in three-month bundles	Not published
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Continuous glucose data with in-app dietitian support	Unlimited messaging with the care team
Money-back Guarantee	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)	None published
Cancellation Policy	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused	Not published among the legal documents

Which should you choose?

Choose Signos if you:

→Want to save $22/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 6.4/10)
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Choose Live Vital if you:

→Want more medication options to choose from
→Value: every protocol is priced openly on one page: glutathione $66/mo, nad+ $83/mo, ghk-cu $99/mo, wolverine and cjc-1295/ipamorelin $116/mo, glow, klow and mots-c $149/mo, tesamorelin $166/mo (checked july 28, 2026)

Get started with Live Vital

Website previews

Signos

Signos website

Live Vital

Live Vital website

Our recommendation

Signos comes out ahead with a higher rating of 7.8/10.

Get started with Signos

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