Signos vs Male Excel
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Signos vs Male Excel: Overview
Choosing between Signos and Male Excel for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. Male Excel also provides both semaglutide and tirzepatide at $194/month with a 7.8/10 rating.
The price difference of $67/month is significant - Signos is the more budget-friendly option, while Male Excel positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$67/mo
Rating Difference
0.0
Winner
Signos
Best For
Budget
Signos
View full Signos review →Rating
7.8/10
Monthly Price
$127Cheaper
Medications
continuous glucose monitoring
Pros
- ✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
- ✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
- ✓Two CGM sensors per month are included in every plan
- ✓HSA/FSA eligible, which matters at these prices
- ✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
- ✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
- ✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
- ✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
- ✓Stress and sleep tracking are built in alongside glucose
Cons
- ✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
- ✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
- ✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
- ✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
- ✗The results guarantee pays out in a free data audit, not money back
- ✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
- ✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm
Male Excel
View full Male Excel review →Rating
7.8/10
Monthly Price
$194
Medications
testosterone cypionatecompounded testosterone creamclomiphene citratethyroid medicationsildenafiltadalafil
Pros
- ✓Prices are published per treatment option rather than hidden behind an intake: Triclozene oral from $95/mo, injectable testosterone cypionate from $120/mo, topical testosterone cream from $132/mo (checked July 28, 2026)
- ✓BBB Accredited with an A+ rating and 7 years in business, plus a real Charlotte, NC street address and a staffed phone line at (833) 625-3392
- ✓Roughly 6,000 Trustpilot reviews averaging 4.5 - a far larger evidence base than the handful of reviews most compounded-medication brands have
- ✓Requires that you have had an in-person physical with vitals taken in the past 3 years before it will prescribe. This rules out some customers, and it is a genuine safety gate that most online hormone clinics skip
- ✓States plainly that prescription testosterone is a Schedule III controlled substance requiring medical monitoring, rather than glossing over it
- ✓ED medications are FDA-approved generics - sildenafil and tadalafil - at $65/month with a $35 first month, not compounded formulations
- ✓No contract, cancel anytime, and treatment costs are FSA/HSA eligible
- ✓The $99/month membership covers unlimited e-visits and unlimited messaging with a dedicated provider, so follow-up questions do not trigger per-visit fees
- ✓Publishes its excluded states openly instead of letting you discover the restriction at checkout
Cons
- ✗The headline 'as low as $95 a month' is roughly half the real cost. A $99/month Medical Membership is mandatory for treatment, so the true entry price is about $194/month, plus a one-time $99 online medical consultation and shipping on top. The membership requirement is disclosed, but only in fine print beneath the plan cards
- ✗The cheapest 'TRT solution' at $95/month is not testosterone. Triclozene is a proprietary compounded blend of clomiphene citrate and thyroid ingredients meant to stimulate your own production. Clomiphene is FDA-approved for ovulation induction in women; prescribing it to men is off-label
- ✗Thyroid medication is bundled into the standard injectable and topical packages by default, described as helping 'with testosterone effectiveness'. Giving thyroid hormone to men without documented hypothyroidism is not supported by Endocrine Society guidance and is worth questioning your provider about directly
- ✗The testosterone cream is explicitly a compounded blend of bioidentical testosterone powder in a Lipoderm base. Compounded preparations are not FDA-approved, and the product page does not mention the FDA at all
- ✗The pricing page claims the cream is '20x more powerful than commercial cream' with no citation, dosing comparison or study attached
- ✗Advertised prices are 60-day supplies billed bi-monthly, so the monthly figures are derived rather than what actually leaves your account
- ✗Not available in Alaska, Arkansas, Connecticut, Hawaii, Idaho, Louisiana, Mississippi, New Hampshire or Rhode Island
- ✗The 'over 100,000 members' figure is the company's own and we found no independent verification of it
- ✗Testosterone therapy carries real risks - it suppresses fertility, can raise red blood cell counts, and is not appropriate for men with prostate or breast cancer or those trying to conceive
Feature-by-feature comparison
| Feature | Signos | Male Excel |
|---|---|---|
| Monthly Price | $127 | $194 |
| Rating | 7.8/10 | 7.8/10 |
| Medications | continuous glucose monitoring | testosterone cypionate, compounded testosterone cream, clomiphene citrate, thyroid medication, sildenafil, tadalafil |
| Insurance Accepted | No | No |
| Support Hours | In-app dietitian chat; hours not published | Not published |
| Live Chat | Available | No |
| Free Shipping | Yes | No |
| Shipping Speed | Free shipping; six-month plans ship in three-month bundles | 2-day shipping on ED medication; hormone orders ship after lab review. Shipping and handling billed on top of plan price |
| Mobile App | Available | No |
| Dedicated Coach | Included | Included |
| Follow-up Frequency | Continuous glucose data with in-app dietitian support | 60-day follow-ups, with unlimited e-visits and messaging included in the $99/month membership |
| Money-back Guarantee | 30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value) | None published; no contract and cancel anytime |
| Cancellation Policy | Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused | No contract, cancel anytime. Medication billed bi-monthly for a 60-day supply |
Which should you choose?
Choose Signos if you:
- →Want to save $67/month with a more affordable option
- →Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
Choose Male Excel if you:
- →Want more medication options to choose from
- →Value: prices are published per treatment option rather than hidden behind an intake: triclozene oral from $95/mo, injectable testosterone cypionate from $120/mo, topical testosterone cream from $132/mo (checked july 28, 2026)
Website previews
Signos
Male Excel
Our recommendation
Signos offers better value at $127/month while maintaining strong ratings.
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