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Signos vs MyDrHank

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Signos vs MyDrHank: Overview

Choosing between Signos and MyDrHank for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. MyDrHank also provides both semaglutide and tirzepatide at $178/month with a 8.1/10 rating.

The price difference of $51/month is significant - Signos is the more budget-friendly option, while MyDrHank positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$51/mo

Rating Difference

0.3

Winner

MyDrHank

Best For

Quality

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

MyDrHank

View full MyDrHank review →

Rating

8.1/10Better

Monthly Price

$178

Medications

semaglutidetirzepatide

Pros

✓The most rigorous evidence handling of any provider on this site: trial figures are attributed to named studies with the population and duration stated, and the site says outright that those results come from FDA-approved formulations rather than the compounded product it sells
✓The weight-loss calculator is labelled 'for illustrative purposes only' and its arithmetic checks out - 20.9% of a 250 lb starting weight is the 52 lbs it displays
✓Prices are published up front: compounded semaglutide from $178/mo, compounded tirzepatide from $240/mo and oral semaglutide from $171/mo (checked July 27, 2026)
✓An oral semaglutide option is available for people who do not want injections, priced below the injectable
✓No commitment is required, the intake takes about five minutes, and the consultation is free
✓Free delivery and no insurance required
✓Longevity, peptide, hair and strength lines are available if you want more than weight care

Cons

✗The affiliate link for this offer lands on MyDrHank's erectile dysfunction promotion, not its GLP-1 pages, so anyone following it for weight loss arrives at the wrong product entirely
✗Trustpilot shows 2.7 out of 5, and although the sample is only 10 reviews, there is no other independent evidence to set against it
✗The '10,000+ patients treated' claim is not supported by any public review footprint we could find
✗The page title on the promotional landing page reads 'MyDrHank Telehealth Plaform' - a misspelling in the site's own title tag
✗No refund or cancellation policy could be found on the pages we checked
✗No published customer phone number or support hours
✗This offer is not available in Kansas, Louisiana, Mississippi, New Mexico, North Dakota or West Virginia
✗As with every compounded GLP-1, the products are not FDA-approved - though MyDrHank is unusually clear in saying so itself

Choose MyDrHank

Feature-by-feature comparison

Feature	Signos	MyDrHank
Monthly Price	$127	$178
Rating	7.8/10	8.1/10
Medications	continuous glucose monitoring	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	In-app dietitian chat; hours not published	Not published
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; six-month plans ship in three-month bundles	Free delivery; timeframe not published
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Continuous glucose data with in-app dietitian support	US-licensed providers review every case; follow-up frequency not published
Money-back Guarantee	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)	None published
Cancellation Policy	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused	No commitment advertised; no formal cancellation policy published

Which should you choose?

Choose Signos if you:

→Want to save $51/month with a more affordable option
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Choose MyDrHank if you:

→Prefer a higher-rated service (8.1/10 vs 7.8/10)
→Want more medication options to choose from
→Value: the most rigorous evidence handling of any provider on this site: trial figures are attributed to named studies with the population and duration stated, and the site says outright that those results come from fda-approved formulations rather than the compounded product it sells

Get started with MyDrHank

Website previews

Signos

Signos website

MyDrHank

MyDrHank website

Our recommendation

MyDrHank comes out ahead with a higher rating of 8.1/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with MyDrHank

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