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Signos vs PeterMD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Signos vs PeterMD: Overview

Choosing between Signos and PeterMD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. PeterMD also provides both semaglutide and tirzepatide at $149/month with a 7.4/10 rating.

With only a $22/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$22/mo

Rating Difference

0.4

Winner

Signos

Best For

Budget

Signos

View full Signos review →

Rating

7.8/10Better

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

PeterMD

View full PeterMD review →

Rating

7.4/10

Monthly Price

$149

Medications

semaglutidetirzepatide

Pros

✓Tiered pricing is published on the product pages: the GLP-1 + B12 program is $149/month at Level 1 ($447 for a 10-12 week supply) and $139/month at Level 2 ($834), with tirzepatide at $149 to start then $249/month billed quarterly (checked July 27, 2026)
✓Free physician consultation and free shipping are included rather than charged separately
✓A price-match guarantee is offered against competitors
✓Compounded semaglutide is paired with B12 in a single injection, which some patients prefer to two separate shots
✓Comprehensive bloodwork is available, which is more than most GLP-1 sellers offer
✓Unlimited provider access is advertised with the plan
✓One of the broader catalogues in the category if you want hormone, sexual health or longevity care from the same clinic

Cons

✗All sales are final once medication is received - PeterMD will not refund or accept returns 'regardless of whether the product remains unused'
✗Damaged or defective items must be reported with a photo within 24 hours of delivery, and the policy states that later requests 'will not be honored'
✗An exit popup pressures an HCG add-on with manufactured scarcity: 'This is the last time you'll see $301... $301 today. $412 if you add it later'
✗The discount maths on the GLP-1 page does not hold up. A '3-Month Plan' shown as 'Regular price: $358.00, Today: $315.00' is labelled '-40%'. That is a 12% reduction, not 40%
✗The same $315 figure appears as PeterMD's own discounted price and, elsewhere on the page, as what 'Others' charge in a '3.8x More Affordable' comparison
✗Tirzepatide is described as 'Clinically proven' although the product sold is a compounded preparation, which has not been through the trials that phrase refers to
✗'The Largest Online Healthcare Clinic in North America' appears in the page title with nothing to support it
✗This offer is not available in Alabama, Arkansas, California, Idaho, Iowa, Kentucky, Louisiana, Massachusetts, Michigan, North Carolina, South Carolina or Texas - twelve states including the two largest

Feature-by-feature comparison

Feature	Signos	PeterMD
Monthly Price	$127	$149
Rating	7.8/10	7.4/10
Medications	continuous glucose monitoring	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	In-app dietitian chat; hours not published	Not published
Live Chat	Available	Available
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; six-month plans ship in three-month bundles	Not published
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Continuous glucose data with in-app dietitian support	Unlimited provider access advertised
Money-back Guarantee	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)	None - all sales are final once medication is received, even if unused
Cancellation Policy	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused	Subscription plans auto-bill; damaged goods must be reported with a photo within 24 hours

Which should you choose?

Choose Signos if you:

→Want to save $22/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 7.4/10)
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Choose PeterMD if you:

→Want more medication options to choose from
→Value: tiered pricing is published on the product pages: the glp-1 + b12 program is $149/month at level 1 ($447 for a 10-12 week supply) and $139/month at level 2 ($834), with tirzepatide at $149 to start then $249/month billed quarterly (checked july 27, 2026)

Get started with PeterMD

Website previews

Signos

Signos website

PeterMD

PeterMD website

Our recommendation

Signos comes out ahead with a higher rating of 7.8/10.

Get started with Signos

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