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Signos vs Trimi Health

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Signos vs Trimi Health: Overview

Choosing between Signos and Trimi Health for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. Trimi Health also provides both semaglutide and tirzepatide at $175/month with a 8.2/10 rating.

With only a $48/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$48/mo

Rating Difference

0.4

Winner

Trimi Health

Best For

Quality

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Trimi Health

View full Trimi Health review →

Rating

8.2/10Better

Monthly Price

$175

Medications

semaglutidetirzepatide

Pros

✓Publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked July 26, 2026
✓Compounded tirzepatide advertised from $125/mo on annual billing, flat across every dose so titrating up does not raise your bill
✓The refund policy is the clearest we have read in this category: cancel any time before a clinician issues your prescription for a full refund with no fees, and a full refund including the consultation fee if a clinician decides you are not a fit
✓It also explains why the cutoff exists, citing USP <795> and <797> rules on patient-specific compounded sterile preparations rather than just asserting that sales are final
✓A 6-month money-back promise: follow the plan and your provider's guidance for six months and, if you have not lost weight, you can request a refund of the plan fees (terms apply)
✓Clinical care is provided by a named network, Arora Health, and the compounded status is disclosed repeatedly - the medications are 'not FDA-approved as drugs'
✓Free overnight shipping, FSA/HSA eligibility, and Affirm, Klarna and Afterpay financing at checkout
✓Damaged or missing deliveries are handled within 24 hours by replacement, refund or carrier claim

Cons

✗The headline $99/mo requires paying $1,188 up front for a year. Billed monthly the same treatment is $175 - a 77% difference the landing page does not put next to the $99
✗The site markets compounded semaglutide as the 'Same active ingredient as Wegovy' and tirzepatide as 'Same as Mounjaro'. That is the exact claim type the FDA cited in its February 2026 warning letter to another telehealth firm, on the basis that it implies the compounded product has been FDA-approved when it has not
✗Efficacy figures are borrowed from trials of the branded drugs and then applied to compounded copies and to individual readers - 'You could lose 44 lbs per the 22% clinical average'. No compounded product has been through those trials
✗The '22% clinical average' overstates the source: tirzepatide's SURMOUNT-1 trial reported about 20.9% mean weight loss at the top 15 mg dose over 72 weeks
✗The '4.5' rating and '50,233+ patients' shown on the site carry no source, and we could not find a Trustpilot profile for the domain to check either figure
✗Once a clinician issues your prescription the order is final and non-refundable, even if the medication has not shipped
✗Trimi publishes provider ranking articles that place Trimi first - 'Cheapest Tirzepatide Providers 2026: Trimi $125/mo of 10 Ranked' - and a guide titled 'How to Cancel TrimRx & Switch to Trimi'. Treat that content as marketing, not independent research
✗No BBB profile and no public complaint history means there is little independent record to check before you commit to an annual plan

Choose Trimi Health

Feature-by-feature comparison

Feature	Signos	Trimi Health
Monthly Price	$127	$175
Rating	7.8/10	8.2/10
Medications	continuous glucose monitoring	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	In-app dietitian chat; hours not published	Support advertised 24/7 via the patient portal
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; six-month plans ship in three-month bundles	Free overnight shipping claimed
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Continuous glucose data with in-app dietitian support	24/7 provider messaging and ongoing check-ins included
Money-back Guarantee	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)	Full refund before a prescription is issued, plus a 6-month money-back promise if you follow the plan and do not lose weight (terms apply)
Cancellation Policy	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused	Cancel any time before your prescription is issued for a full refund; once issued, the order is final

Which should you choose?

Choose Signos if you:

→Want to save $48/month with a more affordable option
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Choose Trimi Health if you:

→Prefer a higher-rated service (8.2/10 vs 7.8/10)
→Want more medication options to choose from
→Value: publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked july 26, 2026

Get started with Trimi Health

Website previews

Signos

Signos website

Trimi Health

Trimi Health website

Our recommendation

Trimi Health comes out ahead with a higher rating of 8.2/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Trimi Health

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