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Signos vs Wisp

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Signos vs Wisp: Overview

Choosing between Signos and Wisp for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Signos focuses on continuous glucose monitoring at $127/month with a rating of 7.8/10. Wisp also provides both semaglutide and tirzepatide at $15/month with a 8.2/10 rating.

The price difference of $112/month is significant - Wisp is the more budget-friendly option, while Signos positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$112/mo

Rating Difference

0.4

Winner

Wisp

Best For

Budget

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Wisp

View full Wisp review →

Rating

8.2/10Better

Monthly Price

$15Cheaper

Medications

ethinyl estradiolnorethindrone acetatelevonorgestreldoxycyclineeflornithineboric acid

Pros

✓This is not a compounded-medication business. Wisp prescribes FDA-approved generics, so you get medicines that have been reviewed for safety, efficacy and quality - a genuine difference from most telehealth brands we cover
✓Prices are low and published: most generic birth control pills from $15/month, the patch from $12, the vaginal ring from $22, levonorgestrel (generic Plan B) from $12.50, DoxyPEP from $22 and boric acid suppositories at $27 (checked July 28, 2026)
✓The provider consult fee is included in the product price rather than charged separately
✓You can have prescriptions sent to a local pharmacy for same-day pickup and apply your insurance there, or take free delivery to all 50 states. Very few telehealth brands let you use insurance at all
✓Wisp also issues a GoodRx discount card for lower out-of-pocket pharmacy costs, which works against its own delivery revenue
✓The formulary page lists the brand-name equivalent for every generic - Cyred EQ alongside Desogen, Apri and Reclipsen, for instance - so you can verify what you are getting
✓Roughly 11,000 Trustpilot reviews with 99% of negative ones answered, usually within a day
✓Broad, genuinely useful catalogue: BV, yeast infection, UTI, herpes, chlamydia, gonorrhea, trichomoniasis, at-home STI testing, birth control, emergency contraception, menopause, PCOS, fertility and migraine
✓DoxyPEP is offered for post-exposure bacterial STI prevention, which reflects current CDC guidance rather than a novelty product
✓Menopause care is a flat $99 online consult covering estrogen and progesterone hormone replacement, with the price stated up front
✓FSA and HSA accepted across most of the range, and orders are processed within 24 hours including weekends

Cons

✗A 4.0 Trustpilot average is the lowest of the well-reviewed brands we cover. Across 11,000 reviews that reflects a real spread of experiences rather than a small-sample fluke
✗Every price is a 'starting at' figure, so the final cost depends on the specific product and supply length you are prescribed
✗The claim that levonorgestrel is '60% cheaper at Wisp than when buying PLAN B at the pharmacy' is not sourced to any price survey or date
✗'Our Doors Are Always Open' sits alongside stated support hours of 9:30am-6:30pm EST Monday to Friday, so the messaging oversells availability
✗Boric acid suppositories are sold for vaginal health but are not FDA-approved for that use, and the evidence base is thinner than for the prescription products alongside them
✗The '1.8 million people' figure is the company's own with no independent verification
✗Hormonal contraception is not suitable for everyone - smokers over 35 and people with a history of blood clots, stroke, certain migraines with aura or oestrogen-sensitive cancers need a clinician's assessment before starting
✗Because prescriptions can be routed to a retail pharmacy, your final cost there may differ from the price shown on the Wisp site

Feature-by-feature comparison

Feature	Signos	Wisp
Monthly Price	$127	$15
Rating	7.8/10	8.2/10
Medications	continuous glucose monitoring	ethinyl estradiol, norethindrone acetate, levonorgestrel, doxycycline, eflornithine, boric acid
Insurance Accepted	No	Yes
Support Hours	In-app dietitian chat; hours not published	9:30am-6:30pm EST, Monday to Friday
Live Chat	Available	Available
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; six-month plans ship in three-month bundles	Free delivery to all 50 states, or same-day pharmacy pickup; orders processed within 24 hours including weekends
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Continuous glucose data with in-app dietitian support	Care team chat available; provider follows up same day by phone or secure chat when needed
Money-back Guarantee	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)	None published
Cancellation Policy	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused	Subscription and one-off purchases available in 1, 3 and 6-month supplies

Which should you choose?

Choose Signos if you:

→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Choose Wisp if you:

→Want to save $112/month with a more affordable option
→Prefer a higher-rated service (8.2/10 vs 7.8/10)
→Want more medication options to choose from
→Need insurance coverage for your treatment
→Value: this is not a compounded-medication business. wisp prescribes fda-approved generics, so you get medicines that have been reviewed for safety, efficacy and quality - a genuine difference from most telehealth brands we cover

Get started with Wisp

Website previews

Signos

Signos website

Wisp

Wisp website

Our recommendation

Wisp comes out ahead with a higher rating of 8.2/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Wisp

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